Abdali, S., De Laere, B., Poulsen, M., Grigorian, M., Lukanidin, E. and Klingelhöfer, J. (2010). Toward Methodology for Detection of Cancer-Promoting S100A4 Protein Conformations in Subnanomolar Concentrations Using Raman and SERS. J. Phys. Chem. C. 114, 7274-7279

Alberici, P., Gaspar, C., Franken, P., Gorski, M. M,, de Vries, I., Scott, R. J., Ristimäki, A., Aaltonen, L. A. and Fodde, R. (2008). Smad4 haploinsufficieny: a matter of dosage. PathoGenetics 1 (1):2

Albrecht, I. and Christofori, G. (2011). Molecular mechanisms of lymphangiogenesis in development and cancer. Int. J. Dev. Biol 55, 483-494

Albrecht, I., Kopfstein, L., Strittmatter, K., Schomber, T., Falkevall, A., Hagberg, C., Lorentz, P., Jeltsch, M., Alitalo, K., Eriksson, U., Christofori, G. and Pietras, K. (2010). Suppressive effects of Vascular Endothelial Growth Factor-B on tumor angiogenesis and growth in a mouse model of pancreatic neuroendocrine tumors. PLoS One 5, e14109

Andolfo, I., De Martino, D., Liguori, L., Petrosino, G., Troncone, G., Tata, N., Galasso, A., Roma, C., Chiancone, F., Zarrilli, S., Arrigoni, G., Staibano, S., Imbimbo, C., Zollo, M. (2011). Correlation of NM23-H1 cytoplasmic expression with metastatic stage in human prostate cancer tissue. Naunyn Schmiedebergs Arch Pharmacol. Oct 384(4-5): 489-98. Epub 2011 May 7

Andolfo, I., Liguori, L., De Antonellis, P., Cusanelli, E., Marinaro, F., Pistollato, F., Garzia, L., De Vita, G., Petrosino, G., Accordi, B., Migliorati, R., Basso, G., Iolascon, A., Cinalli, G. and Zollo, M. (2012). The micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma. Neuro Oncol. May, 14(5):596-612. Epub 2012 Mar 12

Andolfo, I.., Petrosino, G., Vecchione, L., De Antonellis, P., Capasso, M., Montanaro, D., Gemei, M., Troncone, G., Iolascon, A., Orditura, M., Ciardiello, F., De Vita, F. and Zollo, M. (2011). Detection of erbB2 copy number variations in plasma of patients with esophageal carcinoma. BMC Cancer. Apr 11; BMC Cancer. April 11:11:126

Baeriswyl.V. and Christofori, G. (2009). The angiogenic switch in carcinogenesis. 329-337 Sem. Cancer Biol. 19, 329-337

Bastiaannet, E., Sampieri, K., Dekkers, O. M., de Craen, A. J., van Herk-Sukel, M. P., Lemmens, V., van den Broek, C. B., Coebergh, J. W., Herings, R. M., van de Velde, C. J., Fodde, R. and Liefers, G. J. (2012). Use of Aspirin postdiagnosis improves survival for colon cancer patients. Br J Cancer. Mar 27, doi: 10.1038/bjc.2012.101.

Baumann, P., Thiele, W., Cremers, N., Muppala, S., Krachulec, J., Diefenbacher, M., Kassel, O., Mudduluru, G., Allgayer, H., Frame, M. and Sleeman, J. P. (2012). CD24 interacts with and promotes the activity of c-src within lipid rafts in breast cancer cells, thereby increasing integrin-dependent adhesion. Cell Mol Life Sci. 69, 435-448

Berx, G. and van Roy, F. (2009). Involvement of members of the cadherin superfamily in cancer. Cold Spring Harb Perspect Biol. 1: a003129

Bruyère, F., Melen-Lamalle, L., Blacher, S., Roland, G., Thiry, M., Moons, L., Frankenne, F., Carmeliet, P., Alitalo, K., Libert, C., Sleeman, J. P., Foidart, J. M. and Noël, A. (2008). Modeling lymphangiogenesis in a three-dimensional culture system. Nat Methods 5:431-437

Castelletti, D., Fiaschetti, G., Di Dato, V., Ziegler, U., Kumps, C., De Preter, K., Zollo, M., Speleman, F., Shalaby, T., De Martino, D., Berg, T., Eggert, A., Arcaro, A. and Grotzer, M.A. (2010). The quassinoid derivative NBT-272 targets both the AKT and ERK signaling pathways in embryonal tumors. Mol Cancer Ther. Dec;9(12):3145-57, Epub 2010 Oct 1

Chouaib, S., Kieda, C., Benlalam, H., Noman, M. Z., Mami-Chouaib, F. and Rüegg, C. (2010). Endothelial cells as key determinants of the tumor microenvironment: interaction with tumor cells, extracellular matrix and immune killer cells. Crit Rev Immunol. 30(6):529-45

Christofori, G. (2010). Snail1 links transcriptional control with epigenetic regulation (Have you seen…?). EMBO J. 29, 1787-1789

Christofori, G. (2011). Metastatic colon cancer cells negotiate the intravasation notch. (Preview) Cancer Cell 19, 6-8

Cimmino, F., Scoppettuolo, M. N., Carotenuto, M., De Antonellis, P., Dato, V. D., De Vita, G. and Zollo, M. (2012). Norcantharidin impairs medulloblastoma growth by inhibition of Wnt/_-catenin signaling. J Neurooncol. Jan; 106(1):59-70. Epub 2011 Jul 7

Clément-Ziza, M., Gentien, D., Lyonnet, S., Thiery, J.-P., Besmond, C. and Decraene, C. (2009). Evaluation of methods for amplification of picogram amounts of total RNA for whole genome expression profiling. BMC Genomics 10:246

Collins, C. A., Kretzschmar, K. and Watt, F. M. (2011). Reprogramming adult dermis to a neonatal state through epidermal activation of beta-catenin. Development 138, 5189-5199

Connelly, J. T., Ajay Mishra, A., Gautrot, J. E. and Watt, F. M.. (2011). Shape-Induced Terminal Differentiation of Human Epidermal Stem Cells Requires p38 and Is Regulated by Histone Acetylation. PLoS One 6(11):e27259

Connelly, J.T., Gautrot, J.E., Trappmann, B., Tan, D.W., Donati, G., Huck, W.T. and Watt, F.M. (2010). Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions. Nat Cell Biol. 12(7):711-718,Epub 2010 Jun 27

Cremers, N., Deugnier M.A. and Sleeman, J.P. (2010). Loss of CD24 expression promotes ductal branching and enhanced alveoli formation in the murine mammary gland. Cell Mol Life Sci. 67:2311-2322

de Antonellis, P., Medaglia, C., Cusanelli, E., Andolfo, I., Liguori, L., De Vita, G., Carotenuto, M., Bello, A., Formiggini, F., Galeone, A., De Rosa, G., Virgilio, A., Scognamiglio, I., Sciro, M., Basso, G., Schulte, J. H., Cinalli, G., Iolascon, A. and Zollo, M. (2011). MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15/CD133 Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma. PLoS One 6(9):e24584. Epub 2011 Sep 12

De Craene, B., Denecker, G., Vermassen, P., Mauch, C., Derore, A., Virtanen4, I., Jonkers, J., Fuchs, E. and Berx, G. (2012). Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential. Journal National Cancer Institute. Submitted.

De Wever, O., Pauwels, P., De Craene, B., Sabbah, M., Emami, S., Redeuilh, G., Gespach, C., Bracke, M., and Berx, G. (2008). Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front. Histochem Cell Biol. 130:481-49

Ellenbroek, S. I. J., Iden, S. and Collard, J. G.( (2012). Cell polarity proteins and cancer. Seminars in Cancer Biology. in press.

Ellenbroek, S. I. J., Iden, S. and Collard, J. G. (2012). The Rac activator Tiam1 is required for polarized protrusional outgrowth of primary astrocytes by affecting the organization of the microtubule network. Small GTPases 3:11, 1-11

Fagiani, E., Lorentz, P., Kopfstein, L. and Christofori, G. (2011). Angiopoietin-1 and 2 exert antagonistic functions in tumor angiogenesis yet both induce lymphangiogenesis. Cancer Res. (2010) 71, 5717-5727

Fendrich, V., Rehm, J., Waldmann, J., Buchholz, M., Christofori, G., Lauth, M., Slater, E.P. and Bartsch, D.K. (2011). Hedgehog inhibition with cyclopamine represses tumor growth and prolongs survival in a transgenic mouse model of islet cell tumors. Ann. Surg. 253, 546-552

Fodde R. (2009). The stem of cancer. Cancer Cell Feb 3;15(2):87-9

Fodde, R. and Tomlinson, I. (2010). Nuclear beta-catenin expression and Wnt signalling: in defence of the dogma. J Pathol. Jul;221(3):239-41

Forst, B., Hansen, M.T., Klingelhoefer, J., Devitt Møller, H. D., Nielsen, G. H., Grum-Schwensen, B., Ambartsumian, N., Lukanidin, E. and Mariam Grigorian. (2010). Metastasis-Inducing S100A4 and RANTES Cooperate in Promoting Tumor Progression in Mice. PLoS ONE, April, Volume 5, Issue 4, e10374

Foubert, E., De Craene, B. and Berx, G. (2010). Key signalling nodes in mammary gland development and cancer. The Snail1-Twist1 conspiracy in malignant breast cancer progression. Breast Cancer Res. 12:206

Francavilla, C., Cattaneo, P., Berezin, V., Bock, E., Ami, D., de Marco, A., Christofori, G. and Cavallaro, U. (2009). The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking. J. Cell Biol. 187, 1101-1116

Galasso, A, Zollo, M. (2009). The Nm23-H1-h-Prune complex in cellular physiology: a 'tip of the iceberg' protein network perspective. Mol Cell Biochem. 329 (1-2):149-59. Epub 2009 Apr 24.

Garzia, L., Andolfo, I., Cusanelli, E., Marino, N., Petrosino, G., 1, De Martino, D., Esposito, V., Galeone, A., Navas, L., Esposito., S., Gargiulo, S., Fattet, S., Donofrio, V., Cinalli, G., Brunetti, A., Del Vecchio, L., Northcott, P. A., Delattre, O., Taylor, M. D., Iolascon, A. and Zollo, M. (2009). MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma. PLoS ONE. 4: e4998

Gaspar, C., Franken, P., Molenaar, L., Breukel, C., van der Valk, M., Smits, R. and Fodde, R. (2009). A Targeted Constitutive Mutation in the Apc Tumor Suppressor Gene Underlies Mammary But Not Intestinal Tumorigenesis. PLoS Genetics, 5(7):e1000547

Gheldof, A., Vandamme, N., Raspé, E., Gilles, C. and Berx, G. (2012). Unravelling the transcriptional control of ZEB1 induced EMT. Submitted.

Goldie, S. J., Mulder, K., Tan, D. W.-M., Lyons, S. and Watt, F. M. The epidermal stem cell marker FRMD4A regulates tumour growth and metastasis via CD44 and the Hippo pathway. Cancer Research. Accepted.

Grigorian, M., Ambartsumian, N. and Lukanidin, E. (2008). Metastasis-inducing S100A4 protein: implication in non-malignant human pathologies. Curr Mol Med. Sep; 8(6):492-6

Grotegut, S., Kappler, R., Tarimoradi, S., Lehembre, F., Christofori, G. and von Schweinitz, D. (2010). Hepatocyte growth factor protects hepatoblastoma cells from chemotherapy-induced apoptosis by AKT activation. Int. J. Oncol. 36 36, 1261-1267

Grotenhuis, B. A., Dinjens, W. N., Wijnhoven, B. P., Sonneveld, P., Sacchetti, A., Franken, P. F., van Dekken, H., Tilanus, H. W., van Lanschot, J. J., and Fodde R. (2010). Barrett's oesophageal adenocarcinoma encompasses tumour-initiating cells that do not express common cancer stem cell markers. J Pathol. Aug;221(4):379-89.

Grum-Schwensen, B., Klingelhöfer, J., Grigorian, M., Almholt, K., Schnack Nielsen, B., Eugene Lukanidin and Ambartsumian, N. (2010). Lung Metastasis Fails in MMTV-PyMT Oncomice Lacking S100A4 Due to a T-Cell Deficiency in Primary Tumors. Cancer Res. 70(3); 936-947

Hansen, M., Forst, B., Cremers, N., Quagliata, L., Ambartsumian, N., Klingelhöfer, J., Stein, U., Nielsen, G., Scherer, P., Lukanidin, E., Sleeman, J.P. and Grigorian, M. (2012). A downstream target of the metastasis-promoting S100A4 protein, Serum Amyloid A is a potent inducer of tumor metastasis. In preparation.

Iden, S. and Collard, J. G. (2008). Crosstalk between small GTPases and polarity proteins in cell polarization. Nature Reviews. Molecular Cell Biology. 9: 846-859.

Iden, S., van Riel, W. E., Schäfer, R., Song, J.-Y., Frieling, C., Hirose, T., Ohno, S. and Collard, J. G. (2012 Tumor type-dependent function of the Par3 polarity protein in skin tumorigenesis. Cancer Cell. In press.

Imaizumi, N., Monnier, Y., Mirimanoff, R.-O. and Ruegg, C. (2010). Radiotherapy suppresses angiogenesis in mice through TGF-betaRI/ALK5-dependent inhibition of endothelial cell sprouting. PLoS ONE, Jun 11;5(6):e11084

Kaindl, T., Rieger, H., Kaschel, L., Engel, U., Schmaus, A., Sleeman, J.P.* and Tanaka, M.* Spatio-temporal patterns of pancreatic cancer cells expressing CD44 isoforms on supported membranes displaying hyaluronic acid oligomers arrayed with a defined distribution. PLoS ONE. In press.* Equal contribution.

Klingelhoefer, J. (2010). Toward Methodology for Detection of Cancer-Promoting S100A4 Protein Conformations in Subnanomolar Concentrations Using Raman and SERS. J. Phys. Chem. C., 114, 7274-7279

Klingelhoefer J, Grigorian M, Lukanidin E, Ambartsumian N. (2012). Metastasis inhibiting monoclonal antibody targeting the pro-metastatic S100A4 protein. In preparation In preparation.

Klingelhoefer, J. Møller, H.D., Sumer, E.U., Berg, C.H., Poulsen, M., Kiryushko, D., Soroka, V., Ambartsumian, N., Grigorian, M. and Lukanidin, E.M. (2009). Epidermal growth factor receptor ligands as new extracellular targets for the metastasis-promoting S100A4 protein FEBS Journal ,276: 5936-5948

Kretzschmar, K. and Watt, F. M. (2012). Lineage Tracing. Cell 148, 33-45

Kuch, V., Schreiber, C, Thiele, W., Umansky, V. and Sleeman, J. P. (2012). Tumor initiating properties of breast cancer and melanoma cells in vivo are not invariably reflected by spheroid formation in vitro, but can be increased by long-term culturing as adherent monolayers. Int. J. Cancer, In Revision.

Kuonen, F., Laurent, J., Stehle, J.-C., Rausch, T., Faes-van't Hull, E., Biéler, G., Alghisi, G. C., Schwendener, R., Lorusso, G., Andrejevic-Blant, S., Mirimanoff, R.-O. and Ruegg, C.(2012). KITL-dependent mobilization of CD11b+cKit+ myelomonocytic cells promotes post-radiation metastasis. Clin Cancer Res.,In press.

Kuonen, F., Secondini, C. and Rüegg, C. (2012). Emerging Pathways Mediating Growth, Invasion And Metastasis Of Tumors Progressing In An Irradiated Microenvironment. Clin Cancer Res.,In revision.

Kuonen, F., Touvrey, C., Laurent, J. and Ruegg, C. (2010). Fc block treatment, dead cells exclusion, and cell aggregates discrimination concur to prevent phenotypical artifacts in the analysis of subpopulations of tumor-infiltrating CD11b(+) myelomonocytic cells. Cytometry A., Nov., 77(11):1082-90

Laurent, J., Faes-van't Hull, E., Touvrey, C., Kuonen, F., Lan, Q., Doucey, M-A., Ciarloni, L., Imaizumi, N., Alghisi, G.C., Fagiani, E., Zaman, K., Stupp, R., Shibuya, M., Delaloye, J.-F., Christofori, G. and Ruegg, C. (2011). Proangiogenic programming of CD11b+ myelomonocytes in breast cancer by PlGF during differentiation of their hematopoietic progenitors. Cancer Res., 71, 3781-3791

Laurent, J., Hull, E.F,, Touvrey, C., Kuonen, F., Lan, Q., Lorusso, G., Doucey, M. A., Ciarloni, L., Imaizumi, N., Alghisi, G. C., Fagiani, E., Zaman, K., Stupp, R., Shibuya, M., Delaloye, J. F., Christofori, G. and Ruegg, C. (2011). Proangiogenic factor PlGF programs CD11b(+) myelomonocytes in breast cancer during differentiation of their hematopoietic progenitors. Cancer Res., Jun 1;71(11):3781-91. Epub 2011 Apr 20

Laurent, J., Touvrey, C., Botta, F., Kuonen, F. and Ruegg, C. (2011). Emerging paradigms and questions on pro-angiogenic bone marrow-derived myelomonocytic cells. Int J Dev Biol., 55(4-5):527-34

Lehembre, F. and Regenass, U. (2012). Metastatic disease: A drug discovery perspective. Seminars in Cancer Biology, In Press.

Liguori, L., Andolfo, I., De Antonellis, P., Aglio, V., di Dato, V., Marino, N., Ivan Orlotti, N., De Martino, D., Capasso, M., Petrosino, G., Schramm, A., Navas, L., Tonini, G. P., Eggert, A., Iolascon, A. and Zollo, M. (2012). The metallophosphodiesterase Mpped2 impairs tumorigenesis in neuroblastoma. Cell Cycle, Feb 1;11(3):569-81. Epub 2012 Feb 1.

Lorusso, G. and Rüegg, C. (2008). The tumor microenvironment and its contribution to tumor evolution toward metastasis. Histochem Cell Biol., Dec;130(6):1091-103

Lorusso, G., Kuonen, F. and Rüegg, C. (2012) A mouse model of spontaneous breast cancer metastasis to the brain. In preparation.

Lorusso, G. and Rüegg. C. (2012). New insights into the mechanisms of organ-specfic breast cancer metastasis. Semin Cancer Biol., 2012 Apr 5. Epub ahead of print

Luis, T. C., Naber, B. A. and Roozen, P. P., Brugman, M. H., de Haas, E. F., Ghazvini, M., Fibbe, W. E., van Dongen, J. J., Fodde, R. and Staal, F. J. (2011). Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion. Cell Stem Cell, Oct 4;9(4):345-56

Lukanidin, E. and Sleeman, J.P. (2012). Building the niche: The role of the S100 proteins in metastatic growth. Seminars in Cancer Biology, 22: 216-225

Mestdagh, P., Boström, A. K., Impens, F., Fredlund, E., Van Peer, G., De Antonellis, P., von Stedingk, K., Ghesquière, B., Schulte, S., Dews, M., Thomas-Tikhonenko, A., Schulte, J. H., Zollo, M., Schramm, A., Gevaert, K., Axelson, H., Speleman, F. and Vandesompele, J. (2010). The miR-17-92 microRNA cluster regulates multiple components of the TGF-? pathway in neuroblastoma. J. Mol Cell. Dec 10;40(5):762-73

Moller, H., Ralfkjaer, U., Cremers, N., Frankel, M., Troelsgaard Pedersen, R., Klingelhöfer, J., Yanashigawa, H., Grigorian, M., Guldberg, P., Sleeman, J. P., Lukanidin, U. and Ambartsumian, N. (2011). Role of Fibulin-5 (FBLN5) in metastatic organ colonization. Molecular Cancer Research, 9:553-63

Monteiro, J. and Fodde, R. (2010). Cancer stemness and metastasis: Therapeutic consequences and perspectives. European Journal of Cancer, 46:1198-1203

Müller, T., Stein, U., Poletti, A., Garzia, L., Rothley, M., Plaumann, D., Thiele, W., Bauer, M., Galasso, A., Schlag, P., Pankratz, M., Zollo, M. and Sleeman, J. P. (2010). ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients. Oncogene, 29: 2393-2403

Muppala, S., Mudduluru, G., Leupold, J. H., Buergy, D., Sleeman, J.P. and Allgayer, H. (2012). CD24 induces expression of the oncomir miR-21 via Src, and CD24 and Src are both post-transcriptionally downregulated by the tumor suppressor miR-34a. Oncogene, Submitted.

Neeb, A., Wallbaum, S., Novac, N., Scholl, I., Dukovic-Schulze, S., Schreiber, C., Schlag, P., Moll, J., Stein, U. and Sleeman, J. P. (2012). The immediate early gene Ier2 promotes tumor cell motility and metastasis, and predicts poor survival of colorectal carcinoma patients. Oncogene, Aug 16;31(33):3796-806. Epub 2011 Nov 28

Olsen, C. J., Moreira, J., Lukanidin, E. M. and Ambartsumian, N. S. (2010). Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts. BMC Cancer,Aug 19;10:444.

Quagliata, L., Cremers, N., Pytowski, B., Harvey, A., Pettis, R., Thiele, W. and Sleeman, J. P. (2012). Lymph node lymphangiogensis is required for lymph node but not lung metastasis formation in a syngeneic rat breast cancer model. Cancer Research. Submitted.

Raspé, E., Decraene, C. and Berx, G. (2012). Gene expression profiling to dissect the complexity of cancer biology: Pitfalls and promise. Semin. Cancer Biol. Mar 7

Raspé, E., Vandewalle, C., De Craene, B., Vermeulen, P., Dirix, L., Van Roy, F., Goetghebeur, E. and Berx, G. ZEB2/SIP1 a new player in human breast cancer metastasis. Breast Cancer Research. Submitted.

Robanus-Maandag, E. C., Koelink, P. J., Breukel, C., Salvatori, D. C., Jagmohan-Changur, S. C., Bosch, C. A., Verspaget, H. W., Devilee, P., Fodde, R. and Smits, R. (2010). A new conditional Apc-mutant mouse model for colorectal cancer. Carcinogenesis, May;31(5):946-52

Roth, S. [PhD Thesis] (2012). “Silent Waters Run Deep: quiescent stem cells in homeostasis and cancer”. Erasmus University. ISBN 978-90-9026592-6

Roth, S. and Fodde, R. (2011). Quiescent stem cells in intestinal homeostasis and cancer. Cell Commun Adhes., Jun;18(3):33-44

Roth, S. and Fodde, R. (2011). The nature of intestinal stem cells' nurture. EMBO Rep., Jun;12(6):483-4

Roth, S., Franken, P., van Veelen, W., Blonden, L., Raghoebir, L., Beverloo, B., van Drunen, E., Kuipers, E. J., Rottier, R., Fodde, R. and Smits, R. (2009). Generation of a tightly regulated doxycycline-inducible model for studying mouse intestinal biology. Genesis, Jan;47(1):7-13

Rüegg, C., Monnier, Y., Kuonen, F. and Imaizumi, N. (2011). Radiation-induced modifications of the tumor microenvironment promote metastasis. Bull Cancer, Jun; 98(6):47-57

Sampieri, K. and Fodde, R. (2012). Cancer Stem Cell and Metastasis. Semin Cancer Biol., Jun; 22(3):187-93

Sleeman, J. P. (2010). Understanding the mechanisms of lymphangiogenesis: a hope for cancer therapy? Phlebolymphology, 17: 99 - 107

Sleeman, J.P. (2012). The metastatic niche and stromal progression. Cancer and Metastasis Reviews, Epub ahead of print

Sleeman, J.P. (2012). Metastasis: Understanding is the beginning of order in chaos. Seminars in Cancer Biology, 22: 173

Sleeman, J.P., Cady, B., and Pantel, I. (2012). The connectivity of lympogenous and heamtogenous tumor cells dissemination: biological insights and clinical implications. Clin. Exp. Metastasis, Epub ahead of print

Sleeman, J.P., Christofori, G., Fodde, R., Collard, J., Berx, G., Decraene, C. and Rüegg, C. (2012). Concepts of metastasis in flux: the stromal progression model. Seminars in Cancer Biology, 22: 174-186

Sleeman, J. P., Nazarenko, I. and Thiele, W. (2011). Do all roads lead to Rome? Routes to metastasis development. Int. J. Cancer, 128: 2511-26

Sleeman, J. P., Schmid, A. and Thiele, W. (2009). Tumor lymphatics. Seminars in Cancer Biology, 19: 285 - 297

Sleeman, J. P. and Steeg, P. S. (2010). Cancer metastasis as a therapeutic target. European J. Cancer, 46: 1177-1180

Sleeman, J.P. and Thiele, W. (2009). Tumor metastasis and the lymphatic vasculature. Int J. Cancer, 125: 2747 - 2756

Sleeman, J.P. and Thiery, J.P. (2011). The epithelial-mesenchymal transition. Cell, 145: 162.e1

Sofia Vala, I., Martins, L. R., Imaizumi, N., Nunes, R. J., Rino, J., Kuonen, F., Carvalho, L. M., Rüegg, C., Grillo, I. M., Barata, J.T., Mareel, M. and Santos, S. C. (2010). Low doses of ionizing radiation promote tumor growth and metastasis by enhancing angiogenesis. PLoS One, Jun 21;5(6):e11222

Spano, D., Heck, C., De Antonellis, P., Christofori, G. and Zollo, M. (2012). Molecular networks that regulate cancer metastasis. Sem. Cancer Biol., Mar 30. [Epub ahead of print]

Spano, D. and Zollo, M. (2012). Tumor microenvironment: a main actor in the metastasis process. Clin Exp Metastasis, Apr; 29(4):381-95. Epub 2012 Feb 10

Spano, D., Marshall, J.C., Marino, N., De Martino, D., Romano, S., Scoppettuolo, M.N., Bello, A.M., Di Dato, V., Navas, L., De Vita, G., Medaglia, C., Steeg, P.S., and Zollo, M. (2012). Dipyridamole prevents triple-negative breast-cancer progression. Clin Exp Metastasis, Jul 4. Epub ahead of print

Thiele, W., Krishnan, J., Rothley, M., Weih, D., Plaumann, D., Kuch, V., Quagliata, L., Weich, H. and Sleeman, J. P. (2012). VEGFR-3 is expressed on megakaryocyte precursors in the murine bone marrow and plays a regulatory role in megakaryopoiesis. Blood, Epub ahead of print

Tiwari, N., Gheldof, A., Tatari, M. and Christofori, G. (2012). EMT as the ultimate survival mechanism of cancer cells. Sem. Cancer Biol., Mar 8. [Epub ahead of print]

Tiwari, N., Meyer-Schaller, N., Arnold, P., Pachkov, M., van Nimwegen, E. and Christofori, G. (2012). Klf4 is a transcriptional regulator for genes critical for EMT, including Mapk8 (Jnk1). Submitted.

Tiwari, N., Tiwari, V.K., Balwierz, P., Arnold, P., Van Nimwegen, E., Schübeler, D. and Christofori, G. (2012). Polycomb-mediated regulation of epithelial to mesenchymal transition (EMT). In preparation.

Tiwari, N., Waldmeier, Arnold, P., Pachkov, M., Meyer-Schaller, N., van Nimwegen, E. and Christofori, G. (2012). Sox4 is a master regulator of epithelial-mesenchymal transition (EMT) by directly controlling the expression of EMT genes and Ezh2. In revision.

Tremmel, M., Matzke, A., Albrecht, I, Laib, A., Olaku, V., Ballmer-Hofer, K., Christofori, G., Héroult, M., Augustin, H., Ponta, H. and Orian-Rousseau, V. (2009). CD44v6 peptides, potential angiogenesis inhibitors, show that CD44 regulates VEGFR-2. Blood, 114, 5236-5244

Van de Veire, S., Stalmans, I., Heindryckx, F., Oura, H., Tijeras-Raballand, A., Schmidt, T., Loges, S., Albrecht, I., Jonckx, B., Vinckier, S., Van Steenkiste, C., Tugues, S., Rolny, C., De Mol, M., Dettori, D., Hainaud, P., Coenegrachts, L., Contreres, J.O., Van Bergen, T., Cuervo, H., Xiao, W.H., Le Henaff, C., Buysschaert, I., Masouleh, B.K., Geerts, A., Schomber, T., Bonnin, P., Lambert, V., Haustraete, J., Zacchigna, S., Rakic, J.M., Jiménez, W., Noël, A., Giacca, M., Colle, I., Foidart, J.M., Tobelem, G., Morales-Ruiz, M., Vilar, J., Maxwell, P., Vinores, S.A., Carmeliet, G., Dewerchin, M., Claesson-Welsh, L., Dupuy, E., Van Vlierberghe, H., C hristofori, G., Mazzone, M., Detmar, M., Collen, D. and Carmeliet, P. (2010). Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease. Cell, 141, 178-190

Vandewalle, C., Van Roy, F. and Berx, G. (2009). The role of the ZEB family of transcription factors in development and disease. Cell Mol Life Sci., 66:773-787

Van Roy, F., and Berx, G. 2008. The cell-cell adhesion molecule E-cadherin. Cell Mol Life Sci., 65:3756-3788

van Veelen, W., Le, N. H., Helvensteijn, W., Blonden, L., Theeuwes, M., Bakker, E. R., Franken, P. F., van Gurp, L., Meijlink, F., van der Valk, M. A., Kuipers, E. J., Fodde, R. and Smits, R. (2011). ?-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis. Gut, Sep;60(9):1204-12

Waldmeier, L., Meyer-Schaller, N., Diepenbruck, M. and Christofori, G. (2012). Py2T murine breast cancer cells, a versatile model of TGF?-induced EMT in vitro and in vivo. Submitted.

Wallbaum, S., Grau, N., Neeb, A. and Sleeman, J.P. (2009). Cell cycle quiescence can suppress transcription from an ecdysone receptor-based inducible promoter in mammalian cells. Biotechniques, 46 (6):433-40

Wang, Y., Hanifi-Moghaddam, P., Hanekamp, E. E., Kloosterboer, H.J., Franken, P., Veldscholte, J., van Doorn, H. C., Ewing, P. C., Kim, J. J., Grootegoed, J. A., Burger, C. W., Fodde, R. and Blok, L. J. (2009). Progesterone inhibition of Wnt/beta-catenin signaling in normal endometrium and endometrial cancer. Clin Cancer Res., Sep 15;15(18):5784-93

Wicki, A., Herrmann, R. and Christofori, G. (2010). Kras in metastatic colorectal cancer. Swiss Medical Weekly, 140, w13112

Wicki, A., Rochlitz, C., Orleth, A., Ritschard, R., Albrecht, I., Herrmann, R., Christofori, G. and Mamot, C. (2012). Targeting tumor-associated endothelial cells: anti-VEGFR2-immunoliposomes mediate tumor-vessel disruption and induce tumor regression. Clinical Cancer Res., 18, 454-464

Wicki, A., Wild, D., Mansi, R., Orleth, A., M.J., Reubi, J.C., Rochlitz, C., Mäcke, H.R. and Christofori, G. (2012). Synergism of glucagon-like-peptide-1 (GLP-1) receptor targeted therapy with anti-angiogenic compounds in a mouse model of neuroendocrine tumors. Submitted.

Wild, D., Wicki, A., Mansi, R., Béhé, M., Keil, B., Bernhardt, P., Christofori, G., Ell, P. J., and Mäcke, H.R. (2010). Exendin-4-based radiopharmaceuticals for glucagon-like peptide-1 (GLP-1) receptor PET/CT and SPECT/CT imaging. J. Nuclear Med., 51, 1059-1067

Witte, M. H., Dellinger, M. T., McDonald, D. M., Nathanson, S. D., Boccardo, F. M., Campisi, C. C. C., Sleeman, J.P. and Gershenwald, J. E. (2011). Lymphangiogenesis and Hemangiogenesis: Potential Targets for Therapy. J. Surg. Oncol., 103: 489-500

Yilmaz, M. and Christofori, G. (2009). EMT, the cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev., 28: 15-33

Yilmaz, M. and Christofori, G. (2010). Mechanisms of motility in metastasizing cancer cells. Mol Cancer Res., 8, 629-642

Yilmaz, M., Maaß, D., Tiwari, N., Waldmeier, L., Schmidt, P., Lehembre, F. and Christofori, G. (2011). Dlx2 protects from TGF?-induced cell-cycle arrest and apoptosis. EMBO J., 30, 4489-4499

Zibert, J.R., Skov, L., Thyssen, J.P., Jacobsen, G.K., Grigorian, M. (2010). Significance of the S100A4 Protein in Psoriasis. Journal of Investigative Dermatology, 130(1):150-60

Zollo, M., Di Dato, V., Spano, D., De Martino, D., Liguori, L., Marino, N., Vastolo, V., Navas, L., Garrone, B., Mangano, G., Biondi, G. and Guglielmotti, A. (2012). Targeting monocyte chemotactic protein-1 synthesis with bindarit induces tumor regression in prostate and breast cancer animal models. Clin Exp Metastasis, Apr 7. [Epub ahead of print]

Zumsteg, A., Baeriswyl, V., Imaizumi, N., Schwendener, R., Rüegg, C. and Christofori, G. (2009). Myeloid cells contribute to tumor lymphangiogenesis. PLoS One, 4, e7067

Zumsteg, A., Caviezel, C., Strittmatter, K., Garcia-Echeverria, C., Hofmann, F. and Christofori, G. (2012). Repression of malignant tumor progression upon pharmacological IGF-1R blockade in a mouse model of insulinoma. Mol. Cancer Res., In press.

Zumsteg, A. and Christofori, G. (2009). Corrupt policemen: inflammatory cells promote tumor angiogenesis. Curr. Opin. Oncol., 21, 60-70

Zumsteg, A. and Christofori, G. (2011). Myeloid cells and lymphangiogenesis. In: Angiogenesis: From Development to Pathology,(eds. M. Klagsbrun, P. D'Amore), Cold Spring Harbor Press, Cold Spring Harbor, New York, pp. 99-112.

Zumsteg, A., Strittmatter, K., Klewe-Nebenius, D., Antoniadis, H., and Christofori, G. (2010) A bioluminescent mouse model of pancreatic ?-cell carcinogenesis. Carcinogenesis, 31, 1465-1474.

The publication list can also be downloaded here as a word or pdf file.