Ruprecht-Karls-Universität Heidelberg Medizinische Fakultät Mannheim
CBTM: Vaskuläre Biologie und Tumorangiogenese Kontakt, Postanschrift, Impressum Volltext-Suche, E-Mail-Suche, Datenbank-Suche Sitemap  
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CBTM: Vascular Biology and Tumor Angiogenesis

 

 

 

The Department of Vascular Biology and Tumor Angiogenesis is studying the molecular mechanisms of tumor and blood vessel interactions as they relate to angiogenesis, lymphangiogenesis, and tumor metastasis. Presently, there are three groups in the laboratory: The metastasis group studies functional interactions between tumor and endothelial cells. The group aims at deciphering the molecular mechanisms of site-specific metastasis and the role of endothelial cell surface molecules in this process. The second group studies tumor angiogenesis and tumor progression as a spatially and temporally dynamic process. Based on a number of novel tumor models, fundamental questions related to the vascularisation of tumors are addressed. These models will also serve as pre-clinical test systems in order to define the therapeutic window of anti-angiogenic tumor therapies. The molecular mechanisms of lymphangiogenesis are the main research focus of the third group. This group aims at identifying and functionally validating novel candidate genes of the (tumor) lymphangiogenic cascade.

 
 

Contact

Prof. Dr. Hellmut Augustin
Head of Department

Phone HD: +49 6221 42 1500
Phone MA: +49 621 383 9962
e-mail: augustin(at)angiogenese.de