Heidelberg University
Medical Faculty Mannheim
University Hospital Mannheim
CKM receives DFG funding for Project "Prädiktion von Therapieansprechen und Outcome beim lokal fortgeschrittenen Rektum-Karzinom mittels Radiomics und Deep Learning: eine beispielhafte Anwendung für eine allgemein verwendbare, Deep Learning basierte Prozessierungs-Pipeline für die Bild-Klassifikation" read more.
Alena-Kathrin Schnurr presented on our research on AI in medical imaging @ Research Plus forum
read more
Dr. Mathias Davids wins the I. I. Rabi Award of the International Society for Magnetic Resonance in Medicine (ISMRM),
read more, article in local newspaper (Mannheimer Morgen)

MR Coils and Simulation

Group Leader: Valerie Klein, M.Sc. 

Research Profile

The aim of our group is to develop Radio-Frequency (RF) methods for Magnetic Resonance Imaging and Spectroscopy (MRI/MRS) as well as EM simulations for RF safety in the RF and the LF regime. Special focus is set on high resolution proton MRI of kidneys as pre-clinical tool at 3 T and 9.4 T, improvement of Signal-to-Noise-Ratio (SNR)for X-nuclei MRI in the human body at 3 T and for preclinical research at 9.4 T as well as EM simulations for whole body SAR calculations and peripheral nerve stimulations.

    ex-vivo mouse kidney

    Cationized-Ferritin Ex-vivo mouse kidney scanned at 9.4 T with a cryogenically cooled quadrature coil (Bruker BioSpin GmbH, Germany). 25 µm isotropic resolution.

    EM simulations of E field distortions by a detuned 24 channel head coil using different detuning concepts at 3T.

    Sodium/Proton Body Resonator

    3 channel Rx array for chlorine MRI at 9.4 T.

    3 different stacked receive-only coils to a 3 coil base Rx array to enhance prostate MRI at 3T.      



Current research projects

  • High resolution imaging of glomeruli in ex-vivo rodent kidneys at 9.4 and 3T
  • 35Cl/23Na/1H RF resonator systems for preclinical imaging at 9.4T
  • EM-field simulations of novel coil concepts and MRI safety assessment for RF and LF problems
  • Human abdominal, spine and head RF resonators for X-nuclei imaging
  • Organ-dedicated RF resonators
Group members

Interested in joining our group for an internship, Bachelorthesis or Masterthesis? Please contact: Jorge Chacon Caldera



  • Scanners: 
    • 0.5T portable MRI system (Pure Devices GmbH, Germany)
    • 1 and  9.4T pre-clinical MRI Systems (Bruker BioSpin GmbH, Germany)
    • 1.5 and 3T clinical MRI systems (Siemens Healtcare GmbH, Germany)
  • RF laboratory (equipped with 2 NWA)
  • EM simulation software (CST - Computer Simulation Technology AG, Germany)
Recent publications

  • M. Malzacher, R. HuJ. Chacon-Caldera and L. Schad.
    Reducing signal-to-noise ratio degradation due to coil coupling in a receiver array
    for 35CL MRI at 9.4 T: A comparison of matching and decoupling strategies.

    Concept Magn Reson B, in press (2018).
  • J. Chacon-Caldera, A. Fischer, M. Malzacher, Y. Vetter, M. Davids, M. Flöser, C. Stumpf and L. Schad.
    Evaluation of stacked resonators to enhance the performance of a surface
    receive-only arr
    ay for prostate MRI at 3 Tesla.
    Magn Reson Imaging, 53 , p.164-172 (2018).
  • M. Malzacher, M. Davids, L. Schad and J. Chacon-Caldera.
    Evaluating the effects of receive-only arrays in specific absorption rate
    simulations at 3 and 7 T.

    Magn Reson Imaging, 53 , p.7-13 (2018).
  • M. Davids, B. Guérin, M. Malzacher, L. Schad and L. Wald.
    Predicting Magnetostimulation Thresholds in the Peripheral
    Nervous System using Realistic Body Models.

    Sci Rep-Uk, 7, p.5316 (2017).
  • J. Chacon-Caldera, M. Malzacher and L. Schad.
    Partially orthogonal resonators for magnetic resonance imaging.
    Sci Rep-Uk, 7, p.42347 (2017).
  • J. Chacón-Caldera, S. Geraci, P. Krämer, L. Cullen-McEwen, J. Bertram, N. Gretz and L. Schad.
    Fast glomerular quantification of whole ex vivo mouse kidneys using Magnetic Resonance Imaging at 9.4 Tesla.
    Z Med Phys, 26 (1), pp.54-62 (2016).
  • M. Malzacher, R. Kalayciyan, S. Konstandin, S. Haneder and L. Schad.
    Sodium-23 MRI of whole spine at 3 Tesla using a 5-channel receive-only phased-array and a whole-body transmit resonator.
    Z Med Phys, 26 (1), p.95–100 (2016).
Contact: Jorge Chacón Caldera, M.Sc. last modified: 15.01.2020
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