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Spin-lattice relaxation time measurement by means of a TurboFLASH technique

S. Blüml, L. Schad, B. Stepanow and W. Lorenz

Magn Reson Med, 30 (3), pp.289-295

Rapid measurements of in vivo proton spin-lattice relaxation times (T1) in human tissues were performed by magnetic resonance imaging in a 1.5 T whole-body super-conducting MR scanner. The measurements employ serial TurboFLASH imaging (Snapshot-FLASH) with scan times for a single experiment below 4 s. Using centric phase encoding order, an appropriate fitting of the T1-parameter from images with minimum motion artifacts is possible. Comparative T1-determination with a multipoint inversion recovery and spin-echo technique was performed on phantoms containing Gd-DTPA solutions with different T1-values. We found a maximum deviation of 3.3\% for T1 < 1100 ms and of 12.1\% for 1100 ms < T1 < 1700 ms from the results obtained by the IR technique. In vivo measurements of T1-relaxation times were performed in white and grey matter, cerebrospinal fluid, kidney, liver, spleen, muscle, and bone marrow, and yielded values that are in good agreement with reported data.

Contact: Dr. Frank Zöllner last modified: 14.01.2019
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