University of Heidelberg
Faculty of Medicine Mannheim
University Hospital Mannheim
CKM receives DFG funding for Project "Prdiktion von Therapieansprechen und Outcome beim lokal fortgeschrittenen Rektum-Karzinom mittels Radiomics und Deep Learning: eine beispielhafte Anwendung fr eine allgemein verwendbare, Deep Learning basierte Prozessierungs-Pipeline fr die Bild-Klassifikation" read more.
Alena-Kathrin Schnurr presented on our research on AI in medical imaging @ Research Plus forum
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Dr. Mathias Davids wins the I. I. Rabi Award of the International Society for Magnetic Resonance in Medicine (ISMRM),
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Combination of DCE and DSC MRI: Added value in the study of tumor vascularization

M. Heilmann, S. Sourbron, C. Walczak, A. Biffar, J. Vautier, M. Peller and A. Volk

Proceedings 16th Scientific Meeting, International Society for Magnetic Resonance in Medicine, Toronto,, p.446

Combination of DCE and DSC MRI was realized by simultaneous measurement of T1 and T2* kinetics. In a subcutaneous xenograft model implanted in nude mice examined at 4.7T, a 6 kDa CA was suitable for assessing heterogeneous capillary permeability by measuring Ktrans, whereas a 0.5kDa CA yielded perfusion weighted Ktrans values. Furthermore, a description of R2*(t) in the presence of CA leakage was proposed yielding the parameters κ20 and κ21. They are thought to be related to intra-voxel cellular distribution and vascular architecture. Combined DCE-DSC MRI holds potential to improve tumor characterization.

Contact: Prof. Dr. Frank Zöllner last modified: 01.07.2020
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