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Evidence for a vascular contribution to the biexponential signal decay as a function of the b-value in DWI: A verification of the IVIM-model

A. Lemke, L. Schad, B. Stieltjes and F. Laun

Proceedings 17th Scientific Meeting, International Society for Magnetic Resonance in Medicine, Honolulu,, p.1365

DWI of the abdomen was performed using a global suppression of the blood signal to investigate the vascular contribution to the measured ADC and to validate the IVIM-model. The perfusion fraction f and the diffusion coefficient D were extracted from the measured DW-data of five healthy volunteers with and without blood suppression using a biexponential fit. The perfusion fraction f in the suppressed pancreatic and liver tissue decreased significantly (p=0.008), whereas the diffusion coefficient D did not change with suppression (p>0.5). These results verify a vascular contribution to the DWI-measurement at low b-values and validate the IVIM-theory.

Contact: Prof. Dr. Frank Zöllner last modified: 22.05.2019
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