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Fast relaxation induced by SPIO compromises contrast from intermolecular doubleâ??quantum coherence in CRAZEDâ??MRI

E. Mehlin, S. Kirsch and P. Bachert

Proceedings 16th Scientific Meeting, International Society for Magnetic Resonance in Medicine, Toronto,, p.1454

The CRAZED sequence permits detection of signal generated by intermolecular doubleâ??quantum coherence (iDQC). When applied to 1H MRI, a novel type of contrast is obtained, in particular, a positive contrast when superparamagnetic iron oxide particles (SPIOs) are present. We demonstrate that the high T1â??relaxivity of SPIOs can cause spurious signal in CRAZED MRI which cannot be attributed to iDQC.

Contact: Prof. Dr. Frank Zöllner last modified: 20.08.2019
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