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Barke A, Rief W, Korwisi B, Treede RD. Reply to Goebel and Molloy. Pain. 2021 Jan;162(1):322.

Barke A, Korwisi B, Jakob R, Konstanjsek N, Rief W, Treede RD. Classification of chronic pain for the International Classification of Diseases (ICD-11): results of the 2017 International WHO Field Testing. Pain. 2021 Apr 8. Online ahead of print.

Bertocchi I, Eltokhi A, Rozov A, Chi VN, Jensen V, Bus T, Pawlak V, Serafino M, Sonntag H, Yang B, Burnashev N, Li SB, Obenhaus HA, Both M, Niewoehner B, Single FN, Briese M, Boerner T, Gass P, Rawlins JNP, Köhr G, Bannerman DM, Sprengel R. Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice. Commun Biol. 2021 4, 59.

Briševac D, Scholz R, Du D, Elagabani MN, Köhr G, Kornau HC. The small GTPase Arf6 is dysregulated in a mouse model for fragile X syndrome. J Neurochem. 2021 May;157, 666-683.

Enax-Krumova E, Attal N, Bouhassira D, Freynhagen R, Gierthmühlen J, Hansson P, Kuehler B, Maier C, Sachau J, Segerdahl M, Tölle T, Treede RD, Ventzel L, Baron R, Vollert J. Contralateral Sensory and Pain Perception Changes in Patients With Unilateral Neuropathy. Neurology. Jul 27;97(4):e389-402. Epub2021 May 29.

Enax-Krumova E, Baron R, Treede RD, Vollert J. Contralateral sensitisation is not specific for complex regional pain syndrome. Comment on Br J Anaesth 2021; 127: e1e3

Forstenpointner J, Ruscheweyh R, Attal N, Baron R, Bouhassira D, Enax-Krumova EK, Finnerup NB, Freynhagen R, Gierthmühlen J, Hansson P, Jensen TS, Maier C, Rice ASC, Segerdahl M, Tölle T, Treede RD, Vollert J.No pain, still gain (of function): the relation between sensory profiles and the presence or absence of self-reported pain in a large multicenter cohort of patients with neuropathy. Pain. 2021 Mar 1;162(3):718-727.

Gierthmühlen J, Böhmer J, Attal N, Bouhassira D, Freynhagen R, Haanpää M, Hansson P, Jensen TS, Kennedy J, Maier C, Rice ASC, Sachau J, Segerdahl M, Sindrup S, Tölle T, Treede RD, Ventzel L, Vollert J, Baron R. Association of sensory phenotype with quality of life, functionality, and emotional well-being in patients suffering from neuropathic pain Pain. 2021 Sep 23.  Online ahead of print

Goebel A, Birklein F, Brunner F, Clark DJ, Gierthmühlen J, Harden N, Huygeng F, Knudsen L, McCabe C, Lewis J, Maihöfner C, Magerl W, Moseley GL, Terkelsen A, Thomassen I, Bruehl S The Valencia consensus-based adaptation of the IASP complex regional pain syndrome diagnostic criteria 162 (2021) 2346–2348

Hall K T, Vase L, Tobias D K, Dashti H T, Vollert J, Kaptchuk T J, Cook N R. Historical Controls in Randomized Clinical Trials: Opportunities and Challenges. Clinical pharmacology & Therapeutics. 2021 Feb;109(2):343-351.

Johnson S, Marshall A, Hughes D, Homes E, Henrich F, Nurmikko T, Sharma M, Frank B, Bassett P, Marshall A, Magerl W, Goebel A. Mechanistically informed non-invasive peripheral nerve stimulation for peripheral neuropathic pain: a randomised double-blind sham-controlled trial J Transl Med. 2021 Nov 6; 19(1):458

Korwisi B, Hay G, Attal N, Aziz Q, Bennett MI, Benoliel R, Cohen M, Evers S, Giamberardino MA, Kaasa S, Kosek E, Lavand'homme P, Nicholas M, Perrot S, Schug S, Smith BH, Svensson P, Vlaeyen JWS, Wang SJ, Treede RD, Rief W, Barke A.Classification algorithm for the International Classification of Diseases-11 chronic pain classification: development and results from a preliminary pilot evaluation. Pain. 2021 Jul 1;162(7):2087-2096.

Leone C, Di Lionardo A, Di Pietro G, Di Steano G, Falco P, Blockeel AJ, Caspani C, Garcia-Larrea L, Mouraux A, Phillips KG, Treede RD, Truini A How different experimental models of secondary hyperalgesia change the nociceptive flexion reflex. Clin Neurophys 2021 Dec; 132(12): 2989-2995

Li L, Zou Y, Liu B, Yang R, Yang J, Sun M, Li Z, Xu X, Li G, Liu S, Greffrath W, Treede RD, Li G, Liang S. Correction to Contribution of the P2X4 Receptor in Rat Hippocampus to the Comorbidity of Chronic Pain and Depression. ACS Chem Neurosci. 2021 Apr 21;12(8):1463. Epub 2021 Apr 8.

Lionardo AD, Stefano GD, Leonel C, Pietroa GD, Sgrol E, Malara E, Cosentino C, Mollica C, Blockeel AJ, Caspani O, Garcia-Larrea L, Mouraux A, Treede RD, Phillips KG, Valeriani M, Truini A Modulation of the N13 component of the somatosensory evoked potentials in an experimental model of central sensitization in humans Scientifc Reports. 2021 Oct 21; 11(1): 20838

Magerl W, Thalacker E, Vogel S, Schleip R, Klein T, Treede RD, Schilder A.Tenderness of the Skin after Chemical Stimulation of Underlying Temporal and Thoracolumbar Fasciae Reveals Somatosensory Crosstalk between Superficial and Deep Tissues. Life (Basel). 2021 Apr 21;11(5):370.

Meinhardt MW, Pfarr S, Fouquet G, Rohleder C, Meinhardt ML, Barroso-Flores J, Hoffmann R, Jeanblanc J, Paul E, Wagner K, Hansson AC, Köhr G, Meier N, von Ohlen und Halbach O, Bell R, Endepols H, Neumaier B, Schönig K, Bartsch D, Naassila M, Spanagel R, Sommer WH. Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism Sci Adv 2021 Nov 19; 7(47).

Mouraux A, Bloms-Funke P, Boesl I, Caspani O, Chapman SC, Di Stefano G, Finnerup NB, Garcia-Larrea L, Goetz M, Kostenko A, Pelz B, Pogatzki-Zahn E, Schubart K, Stouffs A, Truini A, Tracey I, Troconiz IF, Van Niel J, Vela JM, Vincent K, Vollert J, Wanigasekera V, Wittayer M, Phillips KG, Treede RD. IMI2-PainCare-BioPain-RCT3: a randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by electroencephalography (EEG). Trials. 2021 Jun 17;22(1):404.

Mücke M, Cuhls H, Radbruch L, Baron R, Maier C, Tölle T, Treede RD, Rolke R. Quantitative sensory testing (QST). English version. Schmerz. 2021 Nov; 35 (Suppl 3):153-160.

Nilges P, Rief W, Treede RD, Zenz M. Chronic pain is neither a mental nor a functional disorder but in ICD-11 (finally) an independent diagnosis. Nervenarzt. 2021 Jul;92(7):716-717. Epub 2021 Feb 18.

Nunez-Badinez P, De Leo B, Lauy-Biehlmann A, Hoffmann A, Zollner THM, Saunders PTK, Simitsidellis I, Charrua A, Cruz F, Gomez R, Tejada MA, McMahon SB, Ree LL, Barthas F, Vincent K, Birch J, Meijlink J, Hummelshoy L, Sweeney PJ, Armstrong JD, Treede RD, Nagel J. Preclinical models of endometriosis and interstitial cystitis/bladder pain syndrome: an Innovative Medicines Initiative-PainCare initiative to improve their value for translational research in pelvic pain. Pain 2021 Sep 1; 162(9):2349-2365.

Park T S W, Khan N, Juo A, Nicholson J R, Corradini L, Smith M T. Characterisation of a rat model of mechanical low back pain at an advanced stage using immunohistochemical methods. Clin. Exp. Pharmacol. Physiol. 2021;48:96–106

Pietroa GD, Stefano GD, Leonel C, Lionardo AD, Sgrol E, Blockeel AJ, Caspani O, Garcia-Larrea L, Mouraux A, Phillips KG, Treede RD, Valeriani M. The N13 spinal component of somatosensory evoked potentials is modulated by heterotopic noxious conditioning stimulation suggesting an involvement of spinal wide dynamic range neurons Neurophysiologie Clin 2021 Dec; 51(6): 517-523

Pogatzki-Zahn EM, Liedgens H, Hummelshoj L, Meissner W, Weinmann C, Treede RD, Vincent K, Zahn P, Kaiser U. Developing consensus on core outcome domains for assessing effectiveness in perioperative pain management: results of the PROMPT/IMI-PainCare Delphi Meeting. IMI-PainCare PROMPT consensus panel. Pain. 2021 Mar 3. Online ahead of print. 

Quesada C, Kostenko A, Ho I, Leone C, Nochi Z, Stouffs A, Wittayer M, Caspani O, Brix Finnerup N, Mouraux A, Pickering G, Tracey I, Truini A, Treede RD, Garcia-Larrea L.Human surrogate models of central sensitization: A critical review and practical guide. Eur J Pain. 2021 Aug;25(7):1389-1428.

Russo E, Ma T, Spanagel R, Durstewitz D, Toutounji H, Köhr G. Coordinated prefrontal state transition leads extinction of reward-seeking behaviors J Neurosci. 2021 41, 2406-2419. Epub 2021 Feb 2.

Sachau J, Bruckmueller H, Gierthmühlen J, Magerl W, May D, Binder A, Forstenpointner J, Koetting J, Maier C, Tölle TR, Treede RD, Berthele A, Caliebe A, Diesch C, Flor H, Huge V, Maihöfner C, Rehm S, Kersebaum D, Fabig SC, Vollert J, Rolke R, Stemmler S, Sommer C, Westermann A, Cascorbi I, Baron R. The serotonin receptor 2A (HTR2A) rs6313 variant is associated with higher ongoing pain and signs of central sensitization in neuropathic pain patients.  Eur J Pain. 2021 Mar;25(3):595-611.

Sessler K, Blechschmidt V, Hoheisel U, Mense S, Schirmer L, Treede RD. Spinal cord fractalkine (CX3CL1) signaling is critical for neuronal sensitization in experimental nonspecific, myofascial low back pain. J Neurophysiol. 2021 May 1;125(5):1598-1611. Epub 2021 Feb 17.

Shabes P, C Rosenberger D, Henrich F, Greffrath W, Treede RD, Baumgärtner U, Magerl W. Modality-specific facilitation of noninjurious sharp mechanical pain by topical capsaicin. Pain. 2021 Jan;162(1):275-286.

Singaravelu SK, Hoheisel U, Mense S, Treede RD.Rat dorsal horn neurons primed by stress develop a long-lasting manifest sensitization after a short-lasting nociceptive low back input. Pain Rep. 2021 Mar 4;6(1):e904. eCollection 2021 Jan-Feb.

Srotova I, Kocica J, Vollert J, Kolcava J, Hulova M, Jarkovsky J, Dusek L, Bednarik J, Vlckova E. Sensory and pain modulation profiles of ongoing central neuropathic extremity pain in multiple sclerosis. Eur J Pain. 2021 Mar; 25:573–594

Treede RD. ICD-11: Was ist neu für die Schmerzmedizin? Jatros Neurologie & Psychiatrie 5/2021

Vollert J, Forstenpointner J, Enax-Krumova EK, Gierthmühlen J, Tölle T, Treede RD, Baron R. The need for previous knowledge does not render quantitative sensory testing a "failure" but part of a larger picture of the relationship between nociception and pain. Pain. 2021 Apr 1;162(4):1273-1274

Zinboonyahgoon N, Luansritisakul C, Eiamtanasate S, Duangburong S, Sanansilp V, Korwisi B, Barke A, Rief W, Treede RD. Comparing the ICD-11 chronic pain classification with ICD-10: how can the new coding system make chronic pain visible? A study in a tertiary care pain clinic setting. Pain. 2021 Jul 1;162(7):1995-2001.