Sie befinden sich hier

Inhalt

Publications

Full publication record

https://pubmed.ncbi.nlm.nih.gov/?term=Dieterich+LC&sort=date

Selected publications

Dieterich LC*, Tacconi C*, Ducoli L, Detmar M. The lymphatic vessels in cancer. Physiol Rev. 2022 Oct 1;102(4):1837-1879. * equal contribution

Dieterich LC. Mechanisms of extracellular vesicle-mediated immune evasion in melanoma. Front Immunol. 2022 Aug 23;13:1002551.

Sibler E*, He Y*, Ducoli L, Rihs V, Sidler P, Puig-Moreno C, Frey J, Fujimoto N, Detmar M, Dieterich LC. Immunomodulatory responses of subcapsular sinus floor lymphatic endothelial cells in tumor-draining lymph nodes. Cancers. 2022 Jul 24; 14(15),3602. * equal contribution

Leary N, Walser S, Dieterich LC. Isolation and fluorescent labeling of extracellular vesicles from cultured tumor cells. Methods Mol Biol. 2022;2504:199-206.

Leary N, Walser S, He Y, Pereira P, Gallo A, Collado-Diaz V, Halin C, Peinado H, Dieterich LC. Melanoma-derived extracellular vesicles mediate lymphatic remodeling and impair tumor immunity in draining lymph nodes. J Extracell Vesicles. 2022 Feb; 11(2):e12197.

Fujimoto N, Dieterich LC. Mechanisms and clinical significance of tumor lymphatic invasion. Cells. 2021 Sep; 10(10):2858.

Cousin N*, Cap S*, Dihr M*, Tacconi C, Detmar M, Dieterich LC. Lymphatic PD-L1 expression restricts tumor-specific CD8+ T cell responses. Cancer Res. 2021 Aug 1; 81(15):4133-4144. * equal contribution

Sibler E*, He Y*, Ducoli L, Keller N, Fujimoto N, Dieterich LC, Detmar M. Single-cell transcriptional heterogeneity of lymphatic endothelial cells in normal and inflamed murine lymph nodes. Cells. 2021 Jun 2; 10(6):1371. * equal contribution

Dieterich LC, Bikfalvi A. The tumor organismal environment: role in tumor development and cancer immunotherapy. Semin Cancer Biol. 2020 Oct; 65:197-206.

Dieterich LC*, Tacconi C*, Menzi F, Proulx ST, Kapaklikaya K, Hamada M, Takahashi S, Detmar M. Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis. Angiogenesis. 2020 Aug; 23(3):411-423. * equal contribution

Fujimoto N*, He Y*, D’Addio M, Tacconi C, Detmar M, Dieterich LC. Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes. PLoS Biol. 2020 Apr 6;18(4):e3000704. * equal contribution

Dieterich LC, Kapaklikaya K, Cetintas T, Proulx ST, Commerford CD, Ikenberg K, Bachmann SB, Scholl J, Detmar M. Transcriptional profiling of breast cancer-associated lymphatic vessels reveals VCAM-1 as regulator of lymphatic invasion and permeability. Int J Cancer. 2019 Nov 15;145(10)2804-2815.

Commerford CD*, Dieterich LC*, He Y, Hell T, Montoya-Zegarra JA, Noerrelykke SF, Russo E, Röcken M, Detmar M. Mechanisms of tumor-induced lymphovascular niche formation in draining lymph nodes. Cell Rep. 2018 Dec 26;25(13):3554-3563.e4. * equal contribution

Théry C, Witwer KW, Aikawa E, [and 380 others, including Dieterich LC]. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2018 Nov 23;7(1):1535750.

Ma Q, Dieterich LC, Detmar M. Multiple roles of lymphatic vessels in tumor progression. Curr Opin Immunol 2018 Aug;53:7-12.

Dieterich LC*, Ducoli L*, Shin JW, Detmar M. Distinct transcriptional responses of lymphatic endothelial cells to VEGFR-3 and VEGFR-2 stimulation. Sci Data. 2017 Aug 29;4:170106. * equal contribution

Roudnicky F*, Dieterich LC*, Poyet C, Buser L, Wild P, Tang D, Camenzind P, Ho CH, Otto VI, Detmar M. High expression of insulin receptor on tumor-associated blood vessels in invasive bladder cancer predicts poor overall and progression-free survival. J Pathol. 2017 Jun;242(2):193-205. * equal contribution

Dieterich LC, Ikenberg K, Cetintas T, Kapaklikaya K, Hutmacher C, Detmar M. Tumor-associated lymphatic vessels upregulate PDL1 to inhibit T-cell activation. Front Immunol. 2017 Feb 3;8:66.

Klein S*, Dieterich LC*, Mathelier A, Chong C, Sliwa-Primorac A, Hong YK, Shin JW, Lizio M, Itoh M, Kawaji H, Lassmann T, Daub CO, Arner E, the FANTOM consortium, Carninci P, Hayashizaki Y, Forrest ARR, Wasserman WW, Detmar M. DeepCAGE transcriptomics identify HOXD10 as transcription factor regulating lymphatic endothelial responses to VEGF-C. J Cell Sci. 2016 Jul 1;129(13):2573-85. * equal contribution

Dieterich LC, Detmar M. Tumor lymphangiogenesis and new drug development. Adv Drug Deliv Rev. 2016 Apr 1;99(Pt B):148-60 17.

Dieterich LC*, Klein S*, Mathelier A, Sliwa-Primorac A, Ma Q, Hong YK, Shin JW, Hamada M, Lizio M, Itoh M, Kawaji H, Lassmann T, Daub CO, Arner E, Carninci P, Hayashizaki Y, Forrest ARR, Wasserman WW, Detmar M. DeepCAGE transcriptomics reveal an important role of the transcription factor MAFB in the lymphatic endothelium. Cell Rep. 2015 Nov 17;13(7):1493-504. * equal contribution

Huang H, Langenkamp E, Georganaki M, Loskog A, Fuchs PF, Dieterich LC, Kreuger J, Dimberg A. VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through the inhibition of NF-kappaB-induced endothelial activation. FASEB J. 2015 Jan;29(1):227-38.

Dieterich LC, Seidel CD, Detmar M. Lymphatic vessels: new targets for the treatment of inflammatory diseases. Angiogenesis. 2014 Apr;17(2):359-71.

Dieterich LC*, Huang H*, Massena S, Golenhofen N, Phillipson M, Dimberg A. alphaB-crystallin/HspB5 regulates endothelial-leukocyte interactions by enhancing NF-kappaB-induced upregulation of adhesion molecules ICAM-1, VCAM-1 and E-selectin. Angiogenesis. 2013 Oct;16(4):975-83. * equal contribution

Dieterich LC, Schiller P, Huang H, Wawrousek EF, Loskog A, Wanders A, Moons L, Dimberg A. alphaB-crystallin regulates expansion of CD11b+Gr-1+ cells during tumor progression. FASEB J. 2013 Jan;27(1):151-62.

Dieterich LC*, Mellberg S*, Langenkamp E, Zhang L, Zieba A, Salomäki H, Teichert M, Huang H, Edqvist PH, Kraus T, Augustin HG, Olofsson T, Larsson E, Söderberg O, Molema G, Pontén F, Georgii-Hemming P, Alafuzoff I, Dimberg A. Transcriptional profiling of human glioblastoma vessels indicates a key role for VEGF-A and TGFβ2 in vascular abnormalization. J Pathol. 2012 Nov;228(3):378-90. * equal contribution

Dieterich LC, Dimberg A. Regulation of angiogenesis by the small heat shock protein alphaB-crystallin.  Current Angiogenesis. 2012 Apr;1(1):39-45.