The Department for Cell and Molecular Biology was established in 2008 at the Medical Faculty Mannheim of the University of Heidelberg in collaboration with the German Cancer Research Center (DKFZ).

Our research is centered on different signaling systems that play important roles in the development of organisms and human disease. Many cellular signaling pathways have key roles in tumorigenesis, as well as stem regulation, regeneration and many other areas of biomedical importance. We use modern genomic, genetic and computational approaches to systematically analyze cellular signaling processes. High-throughput screening methods identify novel candidate genes that are further analyzed in various model organisms and human cell types.