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Michaela Ruttorf

Our research focuses on the development and optimisation of sequences and protocols for brain and spinal cord magnetic resonance imaging regarding modalities such as:

  • functional magnetic resonance imaging (fMRI)
  • real-time functional magnetic resonance imaging (rt-fMRI)
  • resting-state functional magnetic resonance imaging (rs-fMRI)
  • diffusion-weighted and diffusion tensor imaging (DTI)
  • network analysis

These techniques are applied to areas of research in fear conditioning, pain, object recognition, learning and memory.

Activation pattern of a single subject participating in an object recognition fMRI experiment after data evaluation
Reconstruction of fibre bundles between different brain areas. The red and green fibres show fibre orientation in Corpus Callosum that connects the brain’s two hemispheres.
Graphical representation of network hierarchy in macaque visual cortex.

Selection of recent publications

  1. S. Diener, F. Nees, M. Wessa, G. Wirtz, U. Frommberger, T. Penga, M. Ruttorf, M. Ruf, C. Schmahl and H. Flor. Reduced amygdala responsivity during conditioning to trauma-related stimuli in posttraumatic stress disorder. Psychophysiology, 53, pp.1460-1471 (2016).
  2. F. Nees, M. Griebe, A. Ebert, M. Ruttorf, B. Gerber, O. Wolf, L. Schad, A. Gass and K. Szabo. Implicit learning in transient global amnesia and the role of stress. Front Behav Neurosci, 10, p.222 (2016).
  3. M. Davids, M. Ruttorf, F. Zöllner and L. Schad. Fast and robust design of time-optimal k-space trajectories in MRI. IEEE T Med Imaging, 34 (2), pp.564-577 (2015).
  4. B. Ubl, C. Kuehner, P. Kirsch, M. Ruttorf, H. Flor and C. Diener. Altered neural reward and loss processing and prediction error signalling in depression. Soc Cogn Affect Neur, 10 (8), pp.1102-1112 (2015).
  5. M. Rance, M. Ruttorf, F. Nees, L. Schad and H. Flor. Neurofeedback of the difference in activation of the anterior cingulate cortex and posterior insular cortex: two functionally connected areas in the processing of pain. Front Behav Neurosci, 8, p.357 (2014).
  6. M. Rance, M. Ruttorf, F. Nees, L. Schad and H. Flor. Real time fMRI feedback of the anterior cingulate and posterior insular cortex in the processing of pain. Hum Brain Mapp, 35 (12), pp.5784-5798 (2014).
  7. R. Cacciaglia, F. Nees, S. Pohlack, M. Ruttorf, T. Winkelmann, S. Witt, V. Nieratschker, M. Rietschel and H. Flor.  A risk variant for alcoholism in the NMDA receptor affects amygdala activity during fear conditioning in humans. Biol Psychol, 94 (1), pp.74-81 (2013).
  8. H. Mochizuki, U. Baumgärtner, S. Kamping, M. Ruttorf, L. Schad, H. Flor, R. Kakigi and R. Treede. Cortico-subcortical activation patterns for itch and pain. Pain, 154 (10), pp.1989-1998 (2013).
  9. S. Pohlack, F. Nees, M. Ruttorf, L. Schad and H. Flor. Activation of the ventral striatum during aversive contextual conditioning in humans. Biol Psychol, 91 (1), pp.74-80 (2012).
  10. S. Pohlack, F. Nees, M. Ruttorf, S. Witt, V. Nieratschker, M. Rietschel and H. Flor. Risk variant for schizophrenia in the neurogranin gene impacts on hippocampus activation during contextual fear conditioning. Mol Psychiatry, 16 (11), pp.1072-1073 (2011).

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