The number of patients affected by chronic inflammatory diseases is constantly increasing. Most of these diseases occur at a young age, are chronic and/or frequently recur and have a huge impact on patients' daily lives. While the number of therapeutic options is increasing, inflammation medicine currently lacks biomarkers. Novel therapies are being developed that can be tailored to individual patients to increase success rates while minimizing the development of resistance and side effects and, thus, enable a precision medicine-based approach.

The Mannheim Comprehensive Inflammation Campus (MCIC) integrates the institutes and clinical departments of the Medical Faculty Mannheim, which already collaborated within the former cross-sectional areas of inflammation medicine, immunology and immunotherapy. The institutes and clinical centers in Mannheim have a long history of expertise in basic science and clinical practice of chronic inflammatory conditions. The MCIC aims to better understand the complexity of inflammatory diseases, to treat patients as efficiently and quickly as possible and to develop innovative personalized therapies.

The MCIC implements interdisciplinary structures such as the Inflammation Board, which advises clinicians on individual treatment options. It connects basic and translational scientists to enable discoveries through a ‘workflow’ from lab to bedside and back. Moreover, it provides a framework that facilitates interaction, translational and basic research and innovation.

The Mannheim Comprehensive Inflammation Campus is a networking platform that attracts and educates talents in clinical and basic immunological research, thus promoting training of the next generation of experts in inflammation medicine. Thus, the MCIC stands for high-quality clinical care. Here, clinical data and samples from defined patient cohorts are collected for research to gain novel insights into markers that correlate with individual disease progression and could guide the development of new therapies for complex inflammatory diseases.

The Mannheim Comprehensive Inflammation Campus comprises the following facilities:

• Mannheim Center for Inflammatory Medicine (MACIM)
• Mannheim Institute for Innate Immunoscience (MI3)
• Center for Inflammatory Disease Control (CIDC)

and the Research Training Group 2727 - InCheck