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Trip (Free-Version)
"Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care."
Pro version with: more systematic reviews, ongoing clinical trials, medical images, clinical videos, link to full-text articles, export function, unlimited related articles (55 $ per year for a single person or institutional license), see https://www.tripdatabase.com/Pro
Special features:
- Filter by quality, differentiated by colour, i.e. "Secondary Evidence" (Systematic Reviews, Guidelines, ...), green, comes first, see evidence pyramid below
- Guideline score, see Info
- Systematic review score, see Info
- Connected (Related) articles function (uses clickstream data, citation data and "Similar articles"), see Info
- Fewer hits than in PubMed, since, among other things, fewer journals are evaluated (e.g. around 550 journals "Primary research"), therefore more focussed and manageable
- additional content beyond "research evidence", see filter graphic below in yellow area
Search options
- AND/OR/NOT search with bracketing or Advanced Search (Pro).
- Wildcard * at the end of words allowed, but automatic singular/plural and synonym search, e.g.: "renal stones" finds "kidney stone", prevention finds prevent and preventing.
- Phrases in inverted commas ("term term")
Note: Truncated phrases not allowed (* is ignored, e.g.: "renal ston*" does not find any hits) - Date filter after the search (FROM)
- Proximity function in the search field via "term term"~number
- Title search via title:term or Advanced Search (Pro)
- PICO search (Note)

Evidence filter (see also graphics below)
- "Secondary Evidence" (green):
- Systematic Reviews, Guidelines
- Evidence Based Synopses: high-quality content that isn't a systematic review, guideline or regulatory guidance
- Regulatory Guidance: official government type outputs such as NICE technology appraisals, FDA drug approvals etc
- "Key primary research" (blue): EvidenceAlerts (selected articles from around 120 top journals, see ACCESSSS) plus articles from NEJM, Lancet, JAMA, BMJ and Annals of internal medicine
- "Controlled Trials" (red): RCTs with Risk of Bias score graphic
- "Primary research" (red): about 550 journals, selected via impact factors, among other things
- see also https://blog.tripdatabase.com/2022/02/13/journal-coverage-in-trip/
Results list and more filters
- PDF linked if technically possible (Pro), otherwise link to PubMed/PMC or publisher's page
- Related Articles (max. 3, more via Pro), Twitter, Bookmark after login
- Export as RIS/CSV or email (after login) (Pro)
- Filter "Clinical Area" bottom left, see screenshot (Pro)

AskTrip - AI-powered clinical question-answering system
“AskTrip is an AI-powered clinical question-answering system built on the trusted foundation of the Trip Database. It delivers evidence-based answers to clinical questions in 30 seconds, drawing from Trip’s extensive search index to ensure the most current and relevant information.”
To use it free of charge via https://www.tripdatabase.com/ask (optimised for mobile devices), you have to be registered and can ask 3 questions per month, as a Pro user an unlimited number. You can also view/search/filter previous questions.
A short summary (Clinical Bottom Line) of the longer answer (Background, Evidence, Conclusion) is displayed, and below this the references that are linked to PubMed or the publisher's website. There is also a "Quality of evidence" rating: High, Good, Moderate, Limited.
Further information can be found at https://blog.tripdatabase.com/2025/06/25/asktrip-is-live-automated-clinical-qa-instantly/.


