Publications

Babin-Ebell Gonçalves A*, Mao Y*, Baljkas T*, Wiedmann F, Eis L, Pilz F, Winkler M, Kürschner-Zacharias SW, Hoffarth M, Funaya C, Shahidi R, Géraud C, Wu CC, Goerdt S, Reiners-Koch PS, Singhal M: A perfusion-independent high-throughput method to isolate liver sinusoidal endothelial cells. Commun Biol, 8(1):22, 2025 (*equally contributing first authors).

Singhal M*,#, Gengenbacher N*, Abdul Pari AA*, Kamiyama M, Hai L, Kuhn B, Kallenberg DM, Kulkarni SR, Camilli C, Preuss SF, Leuchs B, Mogler C, Espinet E, Besemfelder E, Heide D, Heikenwalder M, Sprick MR, Trumpp A, Krijgsveld J, Schlesner M, Hu J, Moss SE, Greenwood J, Augustin HG#: Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastatic colonization. Sci Transl Med, 13:eabe6805, 2021 (*equally contributing first authors; # Co-corresponding authors). Featured as a cover story in the September issue of Science Translational Medicine. 

Gengenbacher N*, Singhal M*, Mogler C, Hai L, Milde L, Abdul Pari AA, Besemfelder E, Fricke C, Baumann D, Gehrs S, Utikal J, Felcht M, Hu J, Schlesner M, Offringa R, Chintharlapalli SR, Augustin HG: Timed Ang2-targeted therapy identifies the Angiopoietin-Tie pathway as key regulator of fatal lymphogenous metastasis. Cancer Discov, 11:424-445, 2021 (*equally contributing first authors).

Singhal M*, Gengenbacher N*, La Porta S*, Gehrs S, Shi J, Kamiyama M, Bodenmiller DM, Fischl A, Schieb B, Besemfelder E, Chintharlapalli S, Augustin HG: Preclinical validation of a novel metastasis-inhibiting Tie1 function-blocking antibody. EMBO Mol Med, 12:e11164, 2020 (*equally contributing first authors).
Accompanied by an editorial by Prof. Robert Kerbel. EMBO Mol Med, 12:e12355, 2020

Abdul Pari AA*, Singhal M*, Hübers C, Mogler C, Schieb B, Gampp A, Gengenbacher N, Reynolds LE, Terhardt D, Géraud C, Utikal J, Thomas M, Goerdt S, Hodivala-Dilke KM, Augustin HG#, Felcht M#: Tumor cell-derived Angiopoietin-2 promotes metastasis in melanoma. Cancer Res, 80:2586-98, 2020 (*equally contributing first authors; # Co-corresponding authors).

Singhal M*, Liu X*, Inverso D, Jiang K, Dai J, He H, Bartels S, Li W, Pari AAA, Gengenbacher N, Besemfelder E, Hui L, Augustin HG#, Hu J#: Endothelial cell fitness dictates the source of regenerating liver vasculature. J Exp Med 215:2497-508, 2018 (*equally contributing first authors; # Co-corresponding authors).
Accompanied by an editorial by Prof. Luisa Iruela-Arispe. J Exp Med 215:2480-482, 2018

Kumar A*, Singhal M*, Chopra C*, Srinivasan S, Surabhi RP, Kanumuri R, Tentu S, Jagadeeshan S, Sundaram S, Ramanathan K, Shankar Pitani R, Muthuswamy B, Abhijit S, Nair AS, Venkatraman G, Rayala SK: Threonine 209 phosphorylation on RUNX3 by Pak1 is a molecular switch for its dualistic functions. Oncogene, 35: 4857-65, 2016 (*equally contributing first authors).

Jagadeeshan S*, Krishnamoorthy YR*, Singhal M*, Subramanian A*, Mavuluri J, Lakshmi A, Roshini A, Baskar G, Ravi M, Joseph LD, Sadasivan K, Krishnan A, Nair AS, Venkatraman G, Rayala SK: Transcriptional regulation of fibronectin by p21-activated kinase-1 modulates pancreatic tumorigenesis. Oncogene 34: 455-64, 2015 (*equally contributing first authors).