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The European Center for Angioscience or ECAS takes a bold and unique approach to prioritize the vasculature itself at center stage of vascular disease pathogenesis. While a damaged end organ needs repair, targeting the vasculature allows preventive normalization.
This change of paradigm, the starting point of what we have termed angioscience, resides in the discovery that blood vessels are not just passive infrastructure, but actively regulate and control organ function and disease development. Research into vascular control of disease development will pave the way towards precision angio-targeted treatment modalities to cure hitherto intractable diseases: This is the mission of ECAS.
2018/19 Annual ECAS Report
We proudly present the first annual report of the European Center for Angioscience (ECAS), which summarizes the scientific and structural work of the first phase of the three-year ECAS inauguration period. Annual Report (pdf)
ECAS' Prof. Dr. Ruiz de Almodóvar has received one of the prestigious Consolidator Grants of the European Research Council, for her project "The Oligo-Vascular Interface: Understanding its Properties and Functions". Almodóvar's group has identified an 'oligo-vascular interface', whereby vessels send out signals to directly control the generation of oligodendrocyte precursor cells. Her research will focus on the identification of molecular interactions between blood vessels and oligodendrocytes during development, homeostasis and in conditions of demyelinating diseases. more...