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The Mannheim Center for Translational Neuroscience (MCTN) at Heidelberg University provides a platform for basic research-oriented, translational and clinical neuroscientists from the Medical Faculty Mannheim to work closely with the Central Institute for Mental Health, the life science research institutions of the University Heidelberg and with the non-university research institutions in the Rhine-Neckar metropolitan area.
Upcoming Talks and Events
News
The innovative field of synthetic immunology, which could lead to fundamentally new approaches and methods in the treatment of infectious diseases and cancer, is the topic of an article in the “Perspectives” section of the journal Nature Nanotechnology. read more …
An international team of researchers has provided new insights into the molecular changes associated with the pathogenesis of inclusion body myositis (IBM), based on single-cell RNA sequencing of muscle biopsies from patients. The scientists found that certain muscle fiber types (type 2A) are particularly susceptible to the pathological processes associated with IBM - associated with genetic stress of the cells and detectable by an increase in corresponding markers indicating pronounced DNA damage in the cell nucleus. In addition, evidence of possible acetylcholinesterase dysfunction has been found in the inflamed muscles of IBM patients. read more …
On May 13-14, 2024, the final symposium of the DFG-funded Research Training Group (RTG) 2350 “Impact of Adverse Childhood Experiences on Psychosocial and Somatic Conditions across the Lifespan” took place at the Cubex One in Mannheim. The two-day symposium provided an update on the current state of knowledge on the effects of adverse childhood experiences. read more …
Christian Schmahl has accepted an appointment as Professor of Psychosomatics and Psychotherapeutic Medicine at the Mannheim Medical Faculty of the University of Heidelberg. He is also now a core member of the MCTN. read more …
Activated T cells, which carry a specific marker protein on their surface, are controlled by natural killer (NK) cells. This is thought to be how the body suppresses destructive immune responses. Researchers at DKFZ and UMM have now discovered that NK cells can interfere with the effect of cancer therapies with immune checkpoint inhibitors in this way. They may also be responsible for the rapid decline of therapeutic CAR-T cells. Interventions in this mechanism could potentially improve the efficacy of these cellular cancer immunotherapies. read more …
Michael Platten has been awarded the 2024 Paul Martini Prize for the development of therapeutic vaccines against malignant brain tumors. The prize is awarded annually by the Paul Martini Foundation, Berlin, for outstanding achievements in clinical-therapeutic drug research. It is endowed with €50,000. read more …
Kontextspalte
Mannheim Center for
Translational Neuroscience
Medical Faculty Mannheim Heidelberg University
Theodor Kutzer-Ufer 1-3
68167 Mannheim
Phone +49 621 383-8066
mctn@ medma.uni-heidelberg.de
Twitter/X @MCTNeuroscience:
twitter.com/MCTNeuroscience
SCIENTIFIC REPORT
CORE MEMBERS
Prof. Dr. Michael Platten
(Director)
Prof. Dr. Andreas Meyer-Lindenberg
(Co-Director)
Prof. Dr. Simon Wiegert
(Co-Director)
ALUMNI
Prof. Dr. Rolf-Detlef Treede
(former MCTN Co-Director)
Prof. Dr. Martin Bohus