A novel vaccination strategy against certain malignant brain tumors could fundamentally improve treatment for patients. Researchers from the DKFZ, Mannheim University Medical Center, Heidelberg University Hospital, and partner institutions have published encouraging long-term results from a clinical trial involving a vaccine that activates the immune system against a common genetic mutation in these tumors. read more …

The GLIORESOLVE consortium came together for its 4^th Plenary Meeting on 23 June 2026, hosted by the Royal College of Surgeons in Ireland (RCSI) in Dublin. The meeting brought together doctoral candidates, principal investigators, consortium partners and associated partners in a hybrid format to review progress across the project as it enters its final phase. read more …

What happens in the brain when rising temperatures increase aggressive behaviour is the central question of Andreas Meyer-Lindenberg, who has been awarded an ERC Advanced Grant for his project “Neuroecological Mechanisms Linking Heat and Aggression Risk” (HOTHEAD). The project focuses on neuronal circuits that jointly regulate aggression and temperature control, and aims to identify a shared biological mechanism underlying heat-related increases in aggression, and its implications for a warming world. read more …

Regular exercise may help reduce the impact of traumatic childhood experiences on the brain and improve stress management over the long term.  read more …

Lukas Bunse investigates novel cell-based therapies for brain tumors at the Medical Faculty Mannheim. read more …

Mannheim Center for Neuromodulation and Neuroprosthetics (MCNN) Expands Research and Translational Neuroscience Activities. read more …

A new study shows that certain T cells specifically respond to amyloid deposits in the brain and may drive inflammatory processes in Alzheimer’s disease. The findings open up new approaches for time-tailored therapies. read more …

How can the brain maintain stable memories when the physical structures underlying them are constantly changing? read more …

A study shows that people with depression and fibromyalgia exhibit nearly identical patterns of impaired emotional regulation and that stress significantly worsens pain and mood. read more …

The results of the EPIsoDE study show that psilocybin can have a significant antidepressant effect. It is important that its use be integrated into psychotherapeutic pre- and post-treatment care. read more …

The new two-photon microscope for intravital fluorescence imaging and photostimulation, based on 3D holography, is now fully installed and operational. read more …

Child and adolescent psychiatrist and psychotherapist Tobias Banaschewski of the Central Institute of Mental Health and neurologist and MCTN director Michael Platten are among the 2025 Highly Cited Researchers! This remarkable distinction highlights their commitment and impactful contributions to advancing their fields.  read more …

Great honor for alcohol research at the CIMH: Prof. Dr. Falk Kiefer was honored with the "European Award for Excellence in Alcohol Research – Helmut Seitz Award" in Brussels. read more …