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Mannheim Center for Translational Neuroscience

The Mannheim Center for Translational Neuroscience (MCTN) at Heidelberg University provides a platform for basic research-oriented, translational and clinical neuroscientists from the Medical Faculty Mannheim to work closely with the Central Institute for Mental Health, the life science research institutions of the University Heidelberg and with the non-university research institutions in the Rhine-Neckar metropolitan area.

Upcoming Talks and Events 

30 March 2023, 4 pm

UMM Grand Rounds: “Upgrading a blood-cerebrospinal fluid barrier model with endothelial cells”, Prof. Christian Schwerk, Pediatrics and Adolescent Medicine 

Online seminar via WebEx (more information)

30 March 2023, 4 pm

UMM Grand Rounds: “All lights on the brain: from molecules to synapses and circuits”, Prof. Simon Wiegert, Neurophysiology 

Online seminar via WebEx (more information)

30 March 2023, 5:15 pm

Neuroscience Colloquium: “Harmonisierte Datenerfassung und strukturierte Befundung für die Medizin der Zukunft: Lessons learned” im Use Case Multiple Sklerose des DIFUTURE Konsortiums – PD Dr. Joachim Havla, Ludwig-Maximilians-Universität Munich, Clinical Neuroimmunology

Location: house 8, 3rd floor, Neurology library (room 1), Universitätsmedizin Mannheim, Theodor-Kutzer-Ufer 1-3, Mannheim 


T cell-independent eradication of experimental glioma

Glioblastoma, an aggressive primary brain tumor type, is considered an immunologically "cold" tumor with sparse infiltration by adaptive immune cells. Immunosuppressive tumor-associated myeloid cells are drivers of tumor progression. Targeting and reprogramming intratumoral myeloid cells induces tumor regression in experimental glioma without requiring adaptive immunity. read more …

Hertie foundation extends the "Hertie Network of Excellence in Clinical Neuroscience" funding program

The network brings together six top sites of clinical brain research and offers career prospects for excellent young researchers. read more ...

What keeps the immune defense in brain tumors functional

Cancer immunotherapies often fail because the immune cells are paralysed by immunosuppressive conditions in the tumor. Scientists from Heidelberg, Mannheim and Tel Aviv have now shown on tissue samples from patients as well as on tumor models in mice that the functionality of the immune defence depends decisively on certain helper cells. read more …

Research on Fatigue in Long-COVID

The chronic exhaustion syndrome "fatigue" occurs as a consequence of surviving a COVID-19 infection. By studying a total of 100 patients, researchers from three scientific institutions in Baden-Württemberg want to gain new insights into fatigue to identify new targets for the therapy of fatigue associated with long-COVID. read more …

Simon Wiegert, new head of the Department of Neurophysiology

Prof. Simon Wiegert has been appointed by the University of Heidelberg to the W3 professorship in neurophysiology and heads the Department of Neurophysiology, since October 2022. He and his team will study the relationship between neuromodulation, neuronal plasticity and long-lasting changes in neuronal networks, with a particular focus on the plasticity of synaptic connections. read more …

John J. Bonica Prize of the IASP for Prof. Rolf-Detlef Treede

Prof. Rolf-Detlef Treede, head of the Department of Neurophysiology has been awarded the John J. Bonica Prize at the World Congress of the International Association for the Study of Pain (IASP). The professional society awards the prize every two years to a person who has made major contribution to pain research or therapy. read more …



Prof. Dr. Rolf-Detlef Treede
(former MCTN Co-Director)

Prof. Dr. Martin Bohus