2020

A surgical mouse model of neonatal pressure overload by transverse aortic constriction.

Malek Mohammadi M, Abouissa A, Heineke J. Nat Protoc. 2021 Feb;16(2):775-790. doi: 10.1038/s41596-020-00434-9. Epub 2020 Dec 16. PMID: 33328612

2019

TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation.

Grund A, Szaroszyk M, Korf-Klingebiel M, Malek Mohammadi M, Trogisch FA, Schrameck U, Gigina A, Tiedje C, Gaestel M, Kraft T, Hegermann J, Batkai S, Thum T, Perrot A, Remedios CD, Riechert E, Völkers M, Doroudgar S, Jungmann A, Bauer R, Yin X, Mayr M, Wollert KC, Pich A, Xiao H, Katus HA, Bauersachs J, Müller OJ, Heineke J. EMBO Mol Med. 2019 Oct;11(10):e10018. doi: 10.15252/emmm.201810018. Epub 2019 Aug 30. PMID: 31468715

Induction of cardiomyocyte proliferation and angiogenesis protects neonatal mice from pressure overload-associated maladaptation.

Malek Mohammadi M, Abouissa A, Azizah I, Xie Y, Cordero J, Shirvani A, Gigina A, Engelhardt M, Trogisch FA, Geffers R, Dobreva G, Bauersachs J, Heineke J. JCI Insight. 2019 Jul 23;5(16):e128336. doi: 10.1172/jci.insight.128336. PMID: 31335322

Inactivation of Sox9 in fibroblasts reduces cardiac fibrosis and inflammation.

Scharf GM, Kilian K, Cordero J, Wang Y, Grund A, Hofmann M, Froese N, Wang X, Kispert A, Kist R, Conway SJ, Geffers R, Wollert KC, Dobreva G, Bauersachs J, Heineke J. JCI Insight. 2019 Jul 16;5(15):e126721. doi: 10.1172/jci.insight.126721. PMID: 31310588

2018

Wohlfeil SA, Häfele V, Dietsch B, Schledzewski K, Winkler M, Zierow J, Leibing T, Malek Mohammadi M, Heineke J, Sticht C, Olsavszky V, Koch PS, Géraud C and Goerdt S. Hepatic endothelial Notch activation protects against liver metastasis by regulating endothelial-tumor cell adhesion independent of angiocrine signaling. Cancer Res. Cancer Res. 2019 Feb 1;79(3):598-610. doi: 10.1158/0008-5472.CAN-18-1752. Epub 2018 Dec 10

doi.org/10.1158/0008-5472.can-18-1752

2017

Malek Mohammadi M, Kattih B, Grund A, Froese N, Korf-Klingebiel M, Gigina A, Schrameck U, Rudat C, Liang Q, Kispert A, Wollert KC, Bauersachs J and Heineke J. The transcription factor GATA4 promotes myocardial regeneration in neonatal mice. EMBO Mol Med. 2017;9:265-279.

doi.org/10.15252/emmm.201606602

Appari M, Breitbart A, Brandes F, Szaroszyk M, Froese N, Korf-Klingebiel M, Mohammadi MM, Grund A, Scharf GM, Wang H, Zwadlo C, Fraccarollo D, Schrameck U, Nemer M, Wong GW, Katus HA, Wollert KC, Müller OJ, Bauersachs J and Heineke J. C1q-TNF-Related Protein-9 Promotes Cardiac Hypertrophy and Failure. Circ Res. 2017;120(1):66-77.

doi.org/10.1161/CIRCRESAHA.116.309398

2015

Zwadlo C, Schmidtmann E, Szaroszyk M, Kattih B, Froese N, Hinz H, Schmitto JD, Widder J, Batkai S, Bähre H, Kaever V, Thum T, Bauersachs J and Heineke J. Antiandrogenic therapy with finasteride attenuates cardiac hypertrophy and left ventricular dysfunction. Circulation. 2015;131(12):1071-81.

doi.org/10.1161/CIRCULATIONAHA.114.012066