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2023
Leikeim, L., Li, H., An, L., Sticht, C., Krämer, B.K., Yard, B., Leipe, J., and Kälsch, A.I. "Adenosine signalling in T-cell activation favours development of IL-17 positive cells with suppressive properties". Immunology. 2023. 169(1): 42-56. doi: 10.1111/imm.13608. PMID: 36373432.
Porth, I., Hirsch, D., Ceribas, Y., Weidner, P., Weichert, W., Götze, T.O., Perner, S., Luley, K., Heyer, C.M., de la Torre, C., Hofheinz, R.D., Lorenzen, S., and Gaiser, T. "Comprehensive biomarker analysis of long-term response to trastuzumab in patients with HER2-positive advanced gastric or gastroesophageal adenocarcinoma". European journal of cancer (Oxford, England : 1990). 2023. 183: 119-130. doi: 10.1016/j.ejca.2023.01.022. PMID: 36848831.
Schmid, C.D., Olsavszky, V., Reinhart, M., Weyer, V., Trogisch, F.A., Sticht, C., Winkler, M., Kürschner, S.W., Hoffmann, J., Ola, R., Staniczek, T., Heineke, J., Straub, B.K., Mittler, J., Schledzewski, K., Ten Dijke, P., Richter, K., Dooley, S., Géraud, C., Goerdt, S., and Koch, P.S. "ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver". Hepatology (Baltimore, Md.). 2023. 77(4): 1211-1227. doi: 10.1002/hep.32641. PMID: 35776660. PMC10026949.
Schott, J., Reitter, S., Lindner, D., Grosser, J., Bruer, M., Shenoy, A., Geiger, T., Mathes, A., Dobreva, G., and Stoecklin, G. "Publisher Correction: Nascent Ribo-Seq measures ribosomal loading time and reveals kinetic impact on ribosome density". Nature methods. 2023. 20(2): 316. doi: 10.1038/s41592-023-01765-7. PMID: 36658280.
2022
Alwahsh, M., Knitsch, R., Marchan, R., Lambert, J., Hoerner, C., Zhang, X., Schalke, B., Lee, D.H., Bulut, E., Graeter, T., Ott, G., Kurz, K.S., Preissler, G., Schölch, S., Farhat, J., Yao, Z., Sticht, C., Ströbel, P., Hergenröder, R., Marx, A., and Belharazem, D. "Metabolic Profiling of Thymic Epithelial Tumors Hints to a Strong Warburg Effect, Glutaminolysis and Precarious Redox Homeostasis as Potential Therapeutic Targets". Cancers. 2022. 14(6). doi: 10.3390/cancers14061564. PMID: 35326714. PMC8945961.
Bitsch, R., Kurzay, A., Özbay Kurt, F., De La Torre, C., Lasser, S., Lepper, A., Siebenmorgen, A., Müller, V., Altevogt, P., Utikal, J., and Umansky, V. "STAT3 inhibitor Napabucasin abrogates MDSC immunosuppressive capacity and prolongs survival of melanoma-bearing mice". Journal for immunotherapy of cancer. 2022. 10(3). doi: 10.1136/jitc-2021-004384. PMID: 35301236. PMC8932276.
Boger, M., Bennewitz, K., Wohlfart, D.P., Hausser, I., Sticht, C., Poschet, G., and Kroll, J. "Comparative Morphological, Metabolic and Transcriptome Analyses in elmo1 (-/-) , elmo2 (-/-) , and elmo3 (-/-) Zebrafish Mutants Identified a Functional Non-Redundancy of the Elmo Proteins". Frontiers in cell and developmental biology. 2022. 10: 918529. doi: 10.3389/fcell.2022.918529. PMID: 35874819. PMC9304559.
Cai, C., Itzel, T., Gaitantzi, H., de la Torre, C., Birgin, E., Betge, J., Gretz, N., Teufel, A., Rahbari, N.N., Ebert, M.P., and Breitkopf-Heinlein, K. "Identification of liver-derived bone morphogenetic protein (BMP)-9 as a potential new candidate for treatment of colorectal cancer". Journal of cellular and molecular medicine. 2022. 26(2): 343-353. doi: 10.1111/jcmm.17084. PMID: 34841646. PMC8743662.
Centner, C., Jerger, S., Mallard, A., Herrmann, A., Varfolomeeva, E., Gollhofer, S., Oesser, S., Sticht, C., Gretz, N., Aagaard, P., Nielsen, J.L., Frandsen, U., Suetta, C., Gollhofer, A., and König, D. "Supplementation of Specific Collagen Peptides Following High-Load Resistance Exercise Upregulates Gene Expression in Pathways Involved in Skeletal Muscle Signal Transduction". Frontiers in physiology. 2022. 13: 838004. doi: 10.3389/fphys.2022.838004. PMID: 35480041. PMC9037237.
Feng, R., Kan, K., Sticht, C., Li, Y., Wang, S., Liu, H., Shao, C., Munker, S., Niess, H., Wang, S., Meyer, C., Liebe, R., Ebert, M.P., Dooley, S., Ding, H., and Weng, H. "A hierarchical regulatory network ensures stable albumin transcription under various pathophysiological conditions". Hepatology (Baltimore, Md.). 2022. 76(6): 1673-1689. doi: 10.1002/hep.32414. PMID: 35257388.
Jauch, A.S., Wohlfeil, S.A., Weller, C., Dietsch, B., Häfele, V., Stojanovic, A., Kittel, M., Nolte, H., Cerwenka, A., Neumaier, M., Schledzewski, K., Sticht, C., Reiners-Koch, P.S., Goerdt, S., and Géraud, C. "Lyve-1 deficiency enhances the hepatic immune microenvironment entailing altered susceptibility to melanoma liver metastasis". Cancer cell international. 2022. 22(1): 398. doi: 10.1186/s12935-022-02800-x. PMID: 36496412. PMC9741792.
Liu, L., An, X., Schaefer, M., Yan, B., de la Torre, C., Hillmer, S., Gladkich, J., and Herr, I. "Nanosilver inhibits the progression of pancreatic cancer by inducing a paraptosis-like mixed type of cell death". Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022. 153: 113511. doi: 10.1016/j.biopha.2022.113511. PMID: 36076598.
Manta, C.P., Leibing, T., Friedrich, M., Nolte, H., Adrian, M., Schledzewski, K., Krzistetzko, J., Kirkamm, C., David Schmid, C., Xi, Y., Stojanovic, A., Tonack, S., de la Torre, C., Hammad, S., Offermanns, S., Krüger, M., Cerwenka, A., Platten, M., Goerdt, S., and Géraud, C. "Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression". Circulation. 2022. 146(23): 1783-1799. doi: 10.1161/circulationaha.121.058615. PMID: 36325910.
Miklánková, P., Linster, E., Boyer, J.B., Weidenhausen, J., Mueller, J., Armbruster, L., Lapouge, K., De La Torre, C., Bienvenut, W., Sticht, C., Mann, M., Meinnel, T., Sinning, I., Giglione, C., Hell, R., and Wirtz, M. "HYPK promotes the activity of the N(α)-acetyltransferase A complex to determine proteostasis of nonAc-X(2)/N-degron-containing proteins". Science advances. 2022. 8(24): eabn6153. doi: 10.1126/sciadv.abn6153. PMID: 35704578. PMC9200280.
Muranyi, W., Schwerk, C., Herold, R., Stump-Guthier, C., Lampe, M., Fallier-Becker, P., Weiß, C., Sticht, C., Ishikawa, H., and Schroten, H. "Immortalized human choroid plexus endothelial cells enable an advanced endothelial-epithelial two-cell type in vitro model of the choroid plexus". iScience. 2022. 25(6): 104383. doi: 10.1016/j.isci.2022.104383. PMID: 35633941. PMC9133638.
Nardozi, D., Palumbo, S., Khan, A.U.M., Sticht, C., Bieback, K., Sadeghi, S., Kluth, M.A., Keese, M., and Gretz, N. "Potential Therapeutic Effects of Long-Term Stem Cell Administration: Impact on the Gene Profile and Kidney Function of PKD/Mhm (Cy/+) Rats". Journal of clinical medicine. 2022. 11(9). doi: 10.3390/jcm11092601. PMID: 35566725. PMC9102853.
Ruberti, C., Feitosa-Araujo, E., Xu, Z., Wagner, S., Grenzi, M., Darwish, E., Lichtenauer, S., Fuchs, P., Parmagnani, A.S., Balcerowicz, D., Schoenaers, S., de la Torre, C., Mekkaoui, K., Nunes-Nesi, A., Wirtz, M., Vissenberg, K., Van Aken, O., Hause, B., Costa, A., and Schwarzländer, M. "MCU proteins dominate in vivo mitochondrial Ca2+ uptake in Arabidopsis roots". The Plant cell. 2022. 34(11): 4428-4452. doi: 10.1093/plcell/koac242. PMID: 35938694. PMC9614509.
Schuller, S., Sieker, J., Riemenschneider, P., Köhler, B., Drucker, E., Weiler, S.M.E., Dauch, D., Sticht, C., Goeppert, B., Roessler, S., Ribback, S., Breuhahn, K., Fend, F., Dombrowski, F., Singer, K., and Singer, S. "HELLS Is Negatively Regulated by Wild-Type P53 in Liver Cancer by a Mechanism Involving P21 and FOXM1". Cancers. 2022. 14(2). doi: 10.3390/cancers14020459. PMID: 35053620. PMC8773711.
Trobisch, T., Zulji, A., Stevens, N.A., Schwarz, S., Wischnewski, S., Öztürk, M., Perales-Patón, J., Haeussler, M., Saez-Rodriguez, J., Velmeshev, D., and Schirmer, L. "Cross-regional homeostatic and reactive glial signatures in multiple sclerosis". Acta neuropathologica. 2022. 144(5): 987-1003. doi: 10.1007/s00401-022-02497-2. PMID: 36112223. PMC9547805.
Velásquez, S.Y., Coulibaly, A., Sticht, C., Schulte, J., Hahn, B., Sturm, T., Schefzik, R., Thiel, M., and Lindner, H.A. "Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis From Systemic Inflammatory Response Syndrome on Intensive Care Unit Admission". Frontiers in immunology. 2022. 13: 864835. doi: 10.3389/fimmu.2022.864835. PMID: 35844509. PMC9280679.
Wang, H., Zhou, Y., Xu, H., Wang, X., Zhang, Y., Shang, R., O'Farrell, M., Roessler, S., Sticht, C., Stahl, A., Evert, M., Calvisi, D.F., Zeng, Y., and Chen, X. "Therapeutic efficacy of FASN inhibition in preclinical models of HCC". Hepatology (Baltimore, Md.). 2022a. 76(4): 951-966. doi: 10.1002/hep.32359. PMID: 35076948. PMC9309180.
Wang, Z., Zeng, Z., Starkuviene, V., Erfle, H., Kan, K., Zhang, J., Gunkel, M., Sticht, C., Rahbari, N., and Keese, M. "MicroRNAs Influence the Migratory Ability of Human Umbilical Vein Endothelial Cells". Genes. 2022b. 13(4). doi: 10.3390/genes13040640. PMID: 35456446. PMC9029696.
Wiggenhauser, L.M., Metzger, L., Bennewitz, K., Soleymani, S., Boger, M., Tabler, C.T., Hausser, I., Sticht, C., Wohlfart, P., Volk, N., Heidenreich, E., Buettner, M., Hammes, H.P., and Kroll, J. "pdx1 Knockout Leads to a Diabetic Nephropathy- Like Phenotype in Zebrafish and Identifies Phosphatidylethanolamine as Metabolite Promoting Early Diabetic Kidney Damage". Diabetes. 2022. 71(5): 1073-1080. doi: 10.2337/db21-0645. PMID: 35100334.
Wohlfart, D.P., Lou, B., Middel, C.S., Morgenstern, J., Fleming, T., Sticht, C., Hausser, I., Hell, R., Hammes, H.P., Szendrödi, J., Nawroth, P.P., and Kroll, J. "Accumulation of acetaldehyde in aldh2.1(-/-) zebrafish causes increased retinal angiogenesis and impaired glucose metabolism". Redox biology. 2022. 50: 102249. doi: 10.1016/j.redox.2022.102249. PMID: 35114580. PMC8818574.
Wohlfeil, S.A., Häfele, V., Dietsch, B., Weller, C., Sticht, C., Jauch, A.S., Winkler, M., Schmid, C.D., Irkens, A.L., Olsavszky, A., Schledzewski, K., Reiners-Koch, P.S., Goerdt, S., and Géraud, C. "Angiogenic and molecular diversity determine hepatic melanoma metastasis and response to anti-angiogenic treatment". Journal of translational medicine. 2022. 20(1): 62. doi: 10.1186/s12967-022-03255-4. PMID: 35109875. PMC8812268.
Yan, B., Liu, L., Zhao, L., Hinz, U., Luo, Y., An, X., Gladkich, J., de la Torre, C., Huang, Z., Schrapel, D., Gross, W., Fortunato, F., Schaefer, M., Gaida, M.M., and Herr, I. "Tumor and stroma COL8A1 secretion induces autocrine and paracrine progression signaling in pancreatic ductal adenocarcinoma". Matrix biology : journal of the International Society for Matrix Biology. 2022. 114: 84-107. doi: 10.1016/j.matbio.2022.11.002. PMID: 36375776.
Zhang, J., Starkuviene, V., Erfle, H., Wang, Z., Gunkel, M., Zeng, Z., Sticht, C., Kan, K., Rahbari, N., and Keese, M. "High-content analysis of microRNAs involved in the phenotype regulation of vascular smooth muscle cells". Scientific reports. 2022. 12(1): 3498. doi: 10.1038/s41598-022-07280-7. PMID: 35241704. PMC8894385.
2021
Bai, L., Pfeifer, T., Gross, W., De La Torre, C., Zhao, S., Liu, L., Schaefer, M., and Herr, I. "Establishment of Tumor Treating Fields Combined With Mild Hyperthermia as Novel Supporting Therapy for Pancreatic Cancer". Frontiers in oncology. 2021. 11: 738801. doi: 10.3389/fonc.2021.738801. PMID: 34804927. PMC8597267.
Barysch, S.V., Stankovic-Valentin, N., Miedema, T., Karaca, S., Doppel, J., Nait Achour, T., Vasudeva, A., Wolf, L., Sticht, C., Urlaub, H., and Melchior, F. "Transient deSUMOylation of IRF2BP proteins controls early transcription in EGFR signaling". EMBO Rep. 2021. 22(3): e49651. doi: 10.15252/embr.201949651. PMID: 33480129. PMC7926235.
Chen, J., Fleming, T., Katz, S., Dewenter, M., Hofmann, K., Saadatmand, A., Kronlage, M., Werner, M.P., Pokrandt, B., Schreiter, F., Lin, J., Katz, D., Morgenstern, J., Elwakiel, A., Sinn, P., Gröne, H.J., Hammes, H.P., Nawroth, P.P., Isermann, B., Sticht, C., Brügger, B., Katus, H.A., Hagenmueller, M., and Backs, J. "CaM Kinase II-δ Is Required for Diabetic Hyperglycemia and Retinopathy but Not Nephropathy". Diabetes. 2021. 70(2): 616-626. doi: 10.2337/db19-0659. PMID: 33239449.
Demirel, E., Arnold, C., Garg, J., Jäger, M.A., Sticht, C., Li, R., Kuk, H., Wettschureck, N., Hecker, M., and Korff, T. "RGS5 Attenuates Baseline Activity of ERK1/2 and Promotes Growth Arrest of Vascular Smooth Muscle Cells". Cells. 2021. 10(7). doi: 10.3390/cells10071748. PMID: 34359918. PMC8306326.
Heil, J., Olsavszky, V., Busch, K., Klapproth, K., de la Torre, C., Sticht, C., Sandorski, K., Hoffmann, J., Schönhaber, H., Zierow, J., Winkler, M., Schmid, C.D., Staniczek, T., Daniels, D.E., Frayne, J., Metzgeroth, G., Nowak, D., Schneider, S., Neumaier, M., Weyer, V., Groden, C., Gröne, H.J., Richter, K., Mogler, C., Taketo, M.M., Schledzewski, K., Géraud, C., Goerdt, S., and Koch, P.S. "Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation". Nature communications. 2021. 12(1): 6963. doi: 10.1038/s41467-021-27161-3. PMID: 34845225. PMC8630019.
Heinkele, F.J., Lou, B., Erben, V., Bennewitz, K., Poschet, G., Sticht, C., and Kroll, J. "Metabolic and Transcriptional Adaptations Improve Physical Performance of Zebrafish". Antioxidants (Basel, Switzerland). 2021. 10(10). doi: 10.3390/antiox10101581. PMID: 34679716. PMC8533608.
Huber, M., Armbruster, L., Etherington, R.D., De La Torre, C., Hawkesford, M.J., Sticht, C., Gibbs, D.J., Hell, R., and Wirtz, M. "Disruption of the N(α)-Acetyltransferase NatB Causes Sensitivity to Reductive Stress in Arabidopsis thaliana". Frontiers in plant science. 2021. 12: 799954. doi: 10.3389/fpls.2021.799954. PMID: 35046984. PMC8761761.
Kan, K., Mu, Y., Bouschbacher, M., Sticht, C., Kuch, N., Sigl, M., Rahbari, N., Gretz, N., Pallavi, P., and Keese, M. "Biphasic Effects of Blue Light Irradiation on Human Umbilical Vein Endothelial Cells". Biomedicines. 2021. 9(7). doi: 10.3390/biomedicines9070829. PMID: 34356893. PMC8301484.
Koch, P.S., Sandorski, K., Heil, J., Schmid, C.D., Kürschner, S.W., Hoffmann, J., Winkler, M., Staniczek, T., de la Torre, C., Sticht, C., Schledzewski, K., Taketo, M.M., Trogisch, F.A., Heineke, J., Géraud, C., Goerdt, S., and Olsavszky, V. "Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation". Frontiers in physiology. 2021. 12: 722394. doi: 10.3389/fphys.2021.722394. PMID: 34658910. PMC8511684.
Olsavszky, V., Sticht, C., Schmid, C.D., Winkler, M., Wohlfeil, S.A., Olsavszky, A., Schledzewski, K., Géraud, C., Goerdt, S., Leibing, T., and Koch, P.S. "Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells". Gene. 2021. 768: 145284. doi: 10.1016/j.gene.2020.145284. PMID: 33130055.
Qi, H., Schmöhl, F., Li, X., Qian, X., Tabler, C.T., Bennewitz, K., Sticht, C., Morgenstern, J., Fleming, T., Volk, N., Hausser, I., Heidenreich, E., Hell, R., Nawroth, P.P., and Kroll, J. "Reduced Acrolein Detoxification in akr1a1a Zebrafish Mutants Causes Impaired Insulin Receptor Signaling and Microvascular Alterations". Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2021. 8(18): e2101281. doi: 10.1002/advs.202101281. PMID: 34278746. PMC8456208.
Thomann, S., Weiler, S.M.E., Wei, T., Sticht, C., De La Torre, C., Tóth, M., Rose, F., Tang, Y., Ritz, T., Ball, C., Glimm, H., Ryschich, E., Schirmacher, P., and Breuhahn, K. "YAP-induced Ccl2 expression is associated with a switch in hepatic macrophage identity and vascular remodelling in liver cancer". Liver international : official journal of the International Association for the Study of the Liver. 2021. 41(12): 3011-3023. doi: 10.1111/liv.15048. PMID: 34459091.
Tóth, M., Wehling, L., Thiess, L., Rose, F., Schmitt, J., Weiler, S.M.E., Sticht, C., De La Torre, C., Rausch, M., Albrecht, T., Grabe, N., Duwe, L., Andersen, J.B., Köhler, B.C., Springfeld, C., Mehrabi, A., Kulu, Y., Schirmacher, P., Roessler, S., Goeppert, B., and Breuhahn, K. "Co-expression of YAP and TAZ associates with chromosomal instability in human cholangiocarcinoma". BMC cancer. 2021. 21(1): 1079. doi: 10.1186/s12885-021-08794-5. PMID: 34615513. PMC8496054.
Winkler, M., Staniczek, T., Kurschner, S.W., Schmid, C.D., Schonhaber, H., Cordero, J., Kessler, L., Mathes, A., Sticht, C., Nessling, M., Uvarovskii, A., Anders, S., Zhang, X.J., von Figura, G., Hartmann, D., Mogler, C., Dobreva, G., Schledzewski, K., Geraud, C., Koch, P.S., and Goerdt, S. "Endothelial GATA4 controls liver fibrosis and regeneration by preventing a pathogenic switch in angiocrine signaling". J Hepatol. 2021. 74(2): 380-393. doi: 10.1016/j.jhep.2020.08.033. PMID: 32916216.
2020
Bär, I., Ast, V., Meyer, D., König, R., Rauner, M., Hofbauer, L.C., and Müller, J.P. "Aberrant Bone Homeostasis in AML Is Associated with Activated Oncogenic FLT3-Dependent Cytokine Networks". Cells. 2020. 9(11). doi: 10.3390/cells9112443. PMID: 33182501. PMC7697865.
Brenna, C., Khan, A.U.M., Picascia, T., Sun, Q., Heuveline, V., and Gretz, N. "New technical approaches for 3D morphological imaging and quantification of measurements". Anat Rec (Hoboken). 2020. 303(10): 2702-2715. doi: 10.1002/ar.24463. PMID: 32533657.
Daniele, C., Nardozi, D., Torelli, A., Khan, A.U.M., and Gretz, N. "Transcutaneous Measurement of Glomerular Filtration Rate in Rodents". Methods Mol Biol. 2020. 2067: 129-137. doi: 10.1007/978-1-4939-9841-8_9. PMID: 31701449.
Gamez, C., Schneider-Wald, B., Schuette, A., Mack, M., Hauk, L., Khan, A.U.M., Gretz, N., Stoffel, M., Bieback, K., and Schwarz, M.L. "Bioreactor for mobilization of mesenchymal stem/stromal cells into scaffolds under mechanical stimulation: Preliminary results". PloS one. 2020. 15(1): e0227553. doi: 10.1371/journal.pone.0227553. PMID: 31923210. PMC6953860.
Loeffler, M.A., Hu, J., Kirchner, M., Wei, X., Xiao, Y., Albrecht, T., De La Torre, C., Sticht, C., Banales, J.M., Vogel, M.N., Pathil-Warth, A., Mehrabi, A., Hoffmann, K., Rupp, C., Köhler, B., Springfeld, C., Schirmacher, P., Ji, J., Roessler, S., and Goeppert, B. "miRNA profiling of biliary intraepithelial neoplasia reveals stepwise tumorigenesis in distal cholangiocarcinoma via the miR-451a/ATF2 axis". J Pathol. 2020. 252(3): 239-251. doi: 10.1002/path.5514. PMID: 32710569.
Lou, B., Boger, M., Bennewitz, K., Sticht, C., Kopf, S., Morgenstern, J., Fleming, T., Hell, R., Yuan, Z., Nawroth, P.P., and Kroll, J. "Elevated 4-hydroxynonenal induces hyperglycaemia via Aldh3a1 loss in zebrafish and associates with diabetes progression in humans". Redox biology. 2020. 37: 101723. doi: 10.1016/j.redox.2020.101723. PMID: 32980661. PMC7519378.
Luiken, S., Fraas, A., Bieg, M., Sugiyanto, R., Goeppert, B., Singer, S., Ploeger, C., Warsow, G., Marquardt, J.U., Sticht, C., De La Torre, C., Pusch, S., Mehrabi, A., Gretz, N., Schlesner, M., Eils, R., Schirmacher, P., Longerich, T., and Roessler, S. "NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis". Oncogene. 2020. 39(15): 3128-3144. doi: 10.1038/s41388-020-1198-3. PMID: 32055024. PMC7142020.
Marquard, S., Thomann, S., Weiler, S.M.E., Bissinger, M., Lutz, T., Sticht, C., Tóth, M., de la Torre, C., Gretz, N., Straub, B.K., Marquardt, J., Schirmacher, P., and Breuhahn, K. "Yes-associated protein (YAP) induces a secretome phenotype and transcriptionally regulates plasminogen activator Inhibitor-1 (PAI-1) expression in hepatocarcinogenesis". Cell Commun Signal. 2020. 18(1): 166. doi: 10.1186/s12964-020-00634-6. PMID: 33097058. PMC7583285.
Sun, Q., Picascia, T., Khan, A.U.M., Brenna, C., Heuveline, V., Schmaus, A., Sleeman, J.P., and Gretz, N. "Application of ethyl cinnamate based optical tissue clearing and expansion microscopy combined with retrograde perfusion for 3D lung imaging". Exp Lung Res. 2020. 46(10): 393-408. doi: 10.1080/01902148.2020.1829183. PMID: 33043719.
2019
Arnold, C., Feldner, A., Zappe, M., Komljenovic, D., De La Torre, C., Ruzicka, P., Hecker, M., Neuhofer, W., and Korff, T. "Genetic ablation of NFAT5/TonEBP in smooth muscle cells impairs flow- and pressure-induced arterial remodeling in mice". Faseb j. 2019. 33(3): 3364-3377. doi: 10.1096/fj.201801594R. PMID: 30383452.
Huang, J., Brenna, C., Khan, A.U.M., Daniele, C., Rudolf, R., Heuveline, V., and Gretz, N. "A cationic near infrared fluorescent agent and ethyl-cinnamate tissue clearing protocol for vascular staining and imaging". Scientific reports. 2019. 9(1): 521. doi: 10.1038/s41598-018-36741-1. PMID: 30679514. PMC6345820.
Saadatmand, A.R., Sramek, V., Weber, S., Finke, D., Dewenter, M., Sticht, C., Gretz, N., Wüstemann, T., Hagenmueller, M., Kuenzel, S.R., Meyer-Roxlau, S., Kramer, M., Sossalla, S., Lehmann, L.H., Kämmerer, S., Backs, J., and El-Armouche, A. "CaM kinase II regulates cardiac hemoglobin expression through histone phosphorylation upon sympathetic activation". Proc Natl Acad Sci U S A. 2019. 116(44): 22282-22287. doi: 10.1073/pnas.1816521116. PMID: 31619570. PMC6825262.
Wei, T., Weiler, S.M.E., Tóth, M., Sticht, C., Lutz, T., Thomann, S., De La Torre, C., Straub, B., Merker, S., Ruppert, T., Marquardt, J., Singer, S., Gretz, N., Schirmacher, P., and Breuhahn, K. "YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells". Oncogene. 2019. 38(27): 5541-5550. doi: 10.1038/s41388-019-0801-y. PMID: 30936457.
2018
González-Vallinas, M., Rodríguez-Paredes, M., Albrecht, M., Sticht, C., Stichel, D., Gutekunst, J., Pitea, A., Sass, S., Sánchez-Rivera, F.J., Lorenzo-Bermejo, J., Schmitt, J., De La Torre, C., Warth, A., Theis, F.J., Müller, N.S., Gretz, N., Muley, T., Meister, M., Tschaharganeh, D.F., Schirmacher, P., Matthäus, F., and Breuhahn, K. "Epigenetically Regulated Chromosome 14q32 miRNA Cluster Induces Metastasis and Predicts Poor Prognosis in Lung Adenocarcinoma Patients". Mol Cancer Res. 2018. 16(3): 390-402. doi: 10.1158/1541-7786.Mcr-17-0334. PMID: 29330288.
Khan, A.U.M., Torelli, A., Wolf, I., and Gretz, N. "AutoCellSeg: robust automatic colony forming unit (CFU)/cell analysis using adaptive image segmentation and easy-to-use post-editing techniques". Scientific reports. 2018. 8(1): 7302. doi: 10.1038/s41598-018-24916-9. PMID: 29739959. PMC5940850.
Sticht, C., De La Torre, C., Parveen, A., and Gretz, N. "miRWalk: An online resource for prediction of microRNA binding sites". PloS one. 2018. 13(10): e0206239. doi: 10.1371/journal.pone.0206239. PMID: 30335862. PMC6193719.
Yuan, X., Li, J., Coulouarn, C., Lin, T., Sulpice, L., Bergeat, D., De La Torre, C., Liebe, R., Gretz, N., Ebert, M.P.A., Dooley, S., and Weng, H.L. "SOX9 expression decreases survival of patients with intrahepatic cholangiocarcinoma by conferring chemoresistance". Br J Cancer. 2018. 119(11): 1358-1366. doi: 10.1038/s41416-018-0338-9. PMID: 30420613. PMC6265288.
2017
Müller, S.M., Wang, S., Telman, W., Liebthal, M., Schnitzer, H., Viehhauser, A., Sticht, C., Delatorre, C., Wirtz, M., Hell, R., and Dietz, K.J. "The redox-sensitive module of cyclophilin 20-3, 2-cysteine peroxiredoxin and cysteine synthase integrates sulfur metabolism and oxylipin signaling in the high light acclimation response". Plant J. 2017. 91(6): 995-1014. doi: 10.1111/tpj.13622. PMID: 28644561.
2016
Becker, A., Klapczynski, A., Kuch, N., Arpino, F., Simon-Keller, K., De La Torre, C., Sticht, C., van Abeelen, F.A., Oversluizen, G., and Gretz, N. "Gene expression profiling reveals aryl hydrocarbon receptor as a possible target for photobiomodulation when using blue light". Scientific reports. 2016. 6: 33847. doi: 10.1038/srep33847. PMID: 27669902. PMC5037386.
Khan, A.U., Mikut, R., and Reischl, M. "A New Feedback-Based Method for Parameter Adaptation in Image Processing Routines". PloS one. 2016. 11(10): e0165180. doi: 10.1371/journal.pone.0165180. PMID: 27764213. PMC5072585.
Khan, A.U., Mikut, R., and Reischl, M. "A Benchmark Data Set to Evaluate the Illumination Robustness of Image Processing Algorithms for Object Segmentation and Classification". PloS one. 2015. 10(7): e0131098. doi: 10.1371/journal.pone.0131098. PMID: 26191792. PMC4508044.