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The Mannheim Institute for Innate Immunoscience (MI3) of Heidelberg University serves as a cross-sectional hub for innovative immunology research with an emphasis on innate immunity. In close connection with the four research areas of the Medical Faculty Mannheim and the University Medical Center Mannheim, the MI3 explores the functions of innate immune cells and their tissue specific cross-talk with the adaptive immune system, non-immune and malignant cells and pathogens.
News
New regulator of gene expression discovered
Biochemists at MI3 and the National Cancer Institute (USA) identified the E3-ligase RNF219 as a novel inhibitor of mRNA deadenylation.
New funding to investigate the dark side of chemotherapy
DFG funds Middle East Cooperation grant to investigate the immunology behind the metastasis-promoting effects of chemotherapy
Insights into the childhood of an mRNA
A newly developed method to investigate early stages in the life of mRNA offers new insights into a poorly characterized mechanism of gene regulation.
How „paralyzed“ immune cells can be reactivated against brain tumors
Brain tumor cells carrying a specific and frequent mutation were found to reprogram infiltrating immune cells and thereby paralyze the body’s own defense against the tumor. Scientists from Heidelberg, Mannheim and Freiburg discovered a mechanism to reactivate the paralyzed immune system and promote its anti-cancer function.
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Kontextspalte
Mannheim Institute for Innate Immunoscience
Medical Faculty Mannheim
Tridomus
Ludolf-Krehl-Straße 13 - 17
D-68167 Mannheim
Phone +49 (0)621/383-71430
mi3@medma.uni-heidelberg.de
Graduate Research Training Group (GRK) 2727/1
Core Members
Adelheid Cerwenka, Prof. Dr. Director
Harald Klüter, Prof. Dr.
- Karen Bieback, Prof. Dr.
- Peter Bugert, Prof. Dr.
- Julia Kzhyshkowska, Prof. Dr.
Thomas Miethke, Prof. Dr.
Michael Neumaier, Prof. Dr.
Co-Director
Georg Stoecklin, Prof. Dr. Dr.
Co-Director
Associate Members
Michael Boettcher, Prof. Dr.
Steven Dooley, Prof. Dr.
Matthias Ebert, Prof. Dr.
- Elke Burgermeister, PD. Dr.
Sascha Gravius, Prof. Dr.
Jörg Heineke, Prof. Dr.
Stefan Klein, PD. Dr.
Bernhard Krämer, Prof. Dr.
- Benito Yard, Prof. Dr.
Holger Lindner, PD Dr.
Sonja Loges, Prof. Dr. Dr.
Jan Nicolay, Prof. Dr.
Michael Platten, Prof. Dr.
Nicole Rotter, Prof. Dr.
Lucas Schirmer, PD. Dr.
Astrid Schmieder, Prof. Dr.
Horst Schroten, Prof. Dr.
Christian Schwerk, Prof. Dr.
Jonathan Sleeman, Prof. Dr.
Marc Sütterlin, Prof. Dr.
- Kai Doberstein, Dr.
- Frederik Marmé, Prof. Dr.
Manfred Thiel, Prof. Dr.
Viktor Umansky, Prof. Dr