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The Department of Cardiovascular Physiology pursues research activities on

  • the diversity of the functions of ion channels, in particular potassium channels, in the circulatory system of different organs (organotypic determination)
  • the plasticity of arterial contractility mechanisms under physiological (postnatal remodeling) and pathophysiological (diabetes) conditions and the regulation of these processes by miRNA
  • the response of vascular cells to changes of physical forces in their environment, in particular cell-matrix interactions in cell culture models mimicking changes in vessel wall rigidity
  • the role of the endothelial glycocalyx in barrier function under persistent flow to preserve the physiological glycocalyx surface layer and to induce a regain of typical endothelial cell surface modifications