Publications with MCTN Affiliation 2025

1. Phosphorylated tau 181 and 217 are elevated in serum and muscle of patients with amyotrophic lateral sclerosis.
   Abu-Rumeileh S, Scholle L, Mensch A, Grosskopf H, Ratti A, Kolsch A, Stoltenburg-Didinger G, Conrad J, De Gobbi A, Barba L, Steinacker P, Klafki HW, Oeckl P, Halbgebauer S, Stapf C, Posa A, Kendzierski T, Silani V, Hausner L, Ticozzi N, Froelich L, Weishaupt JH, Verde F, and Otto M. Nat Commun. 2025. 16(1):2019.
   DOI: 10.1038/s41467-025-57144-7.
2. Mass-Guided Single-Cell MALDI Imaging of Low-Mass Metabolites Reveals Cellular Activation Markers.
   Cairns JL, Huber J, Lewen A, Jung J, Maurer SJ, Bausbacher T, Schmidt S, Levkin PA, Sevin D, Gopfrich K, Koch P, Kann O, and Hopf C. Adv Sci (Weinh). 2025. 12(5):e2410506.
   DOI: 10.1002/advs.202410506.
3. Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen.
   Chih YC, Dietsch AC, Koopmann P, Ma X, Agardy DA, Zhao B, De Roia A, Kourtesakis A, Kilian M, Kramer C, Suwala AK, Stenzinger M, Boenig H, Blum A, Pienkowski VM, Aman K, Becker JP, Feldmann H, Bunse T, Harbottle R, Riemer AB, Liu HK, Etminan N, Sahm F, Ratliff M, Wick W, Platten M, Green EW, and Bunse L. Nat Commun. 2025. 16(1):1262.
   DOI: 10.1038/s41467-025-56547-w.
4. Preferential C-nociceptor stimulation facilitates peripheral axon reflex flare, but not secondary mechanical hyperalgesia.
   Daneffel L, Rukwied R, Schmelz M, Ruppen W, and Schneider T. Front Pain Res (Lausanne). 2025. 6:1556429.
   DOI: 10.3389/fpain.2025.1556429.
5. Exploring the value of a well-established conditioned pain modulation paradigm in women: a Translational Research in Pelvic Pain (TRiPP) study.
   Demetriou L, Perro D, Coxon L, Krassowski M, Lunde CE, Ferreira-Gomes J, Charrua A, Abreu-Mendes P, Arendt-Nielsen L, Aziz Q, Birch J, Garbutt K, Horne A, Hoffman A, Hummelshoj L, Meijlink J, Obendorf M, Pogatzki-Zahn E, Sasamoto N, Terry K, Treede RD, Vitonis A, Vollert J, Rahmioglu N, Becker CM, Cruz F, Missmer SA, Zondervan K, Sieberg CB, Nagel J, and Vincent K. Front Pain Res (Lausanne). 2025. 6:1439563.
   DOI: 10.3389/fpain.2025.1439563.
6. Andexanet alfa in patients with factor Xa inhibitor-associated intracranial hemorrhage: The prospective observational multicenter ASTRO-DE study.
   Diener HC, Kuklik N, Husing A, Alonso A, Nabavi DG, Poli S, Gabriel MM, Maier IL, and Grans J. Int J Stroke. 2025:17474930251317385.
   DOI: 10.1177/17474930251317385.
7. Left atrial appendage occlusion in vulnerable oldest-old patients - Effectiveness and safety in a large single-center registry.
   Fastner C, Tavas E, Hetjens S, Kruska M, Ansari U, Behnes M, Kuschyk J, Duerschmied D, Burkhardt H, Alonso A, and Akin I. J Neurol Sci. 2025. 473:123521.
   DOI: 10.1016/j.jns.2025.123521.
8. In vivo composition of the mitochondrial nucleoid in mice.
   Garcia-Villegas R, Odenthal F, Giannoula Y, Bonekamp NA, Kuhl I, Park CB, Spahr H, Motori E, Levander F, and Larsson NG. Biochim Biophys Acta Mol Cell Res. 2025. 1872(6):119955.
   DOI: 10.1016/j.bbamcr.2025.119955.
9. Increasing the smoking cessation success rate by enhancing improvement of self-control through sleep-amplified memory consolidation: protocol of a randomized controlled, functional magnetic resonance study.
   Gerhardt S, Kroth M, Seeger A, Schmitt R, Fritz H, Diring L, Shevchenko Y, Ersche KD, Feld G, and Vollstadt-Klein S. BMC Psychol. 2025. 13(1):157.
   DOI: 10.1186/s40359-025-02482-w.
10. Somatosensory profiling to differentiate distinct painful diseases of the pancreas-a quantitative sensory testing case-control study.
    Goltl P, Merz P, Schneider A, Ebert MP, Hirth M, and Magerl W. Pain. 2025.
    DOI: 10.1097/j.pain.0000000000003601.
11. Identifying similar populations across independent single cell studies without data integration.
    Gonzalez-Velasco O, Simon M, Yilmaz R, Parlato R, Weishaupt J, Imbusch CD, and Brors B. NAR Genom Bioinform. 2025. 7(2):lqaf042.
    DOI: 10.1093/nargab/lqaf042.
12. Deep MALDI-MS spatial omics guided by quantum cascade laser mid-infrared imaging microscopy.
    Gruber L, Schmidt S, Enzlein T, Vo HG, Bausbacher T, Cairns JL, Ucal Y, Keller F, Kerndl M, Sammour DA, Sharif O, Schabbauer G, Rudolf R, Eckhardt M, Iakab SA, Bindila L, and Hopf C. Nat Commun. 2025. 16(1):4759.
    DOI: 10.1038/s41467-025-59839-3.
13. From Smoking to Vaping: The Motivation for E-cigarette Use at the Neurobiological Level-A Functional Magnetic Resonance Imaging Study.
    Grundinger N, Andreas M, Lohner V, Schneider S, Mons U, and Vollstadt-Klein S. Nicotine Tob Res. 2025. 27(7):1236-1246.
    DOI: 10.1093/ntr/ntae273.
14. Metabolomic reprogramming of the tumor microenvironment by dual arginase inhibitor OATD-02 boosts anticancer immunity.
    Grzybowski MM, Ucal Y, Muchowicz A, Rejczak T, Kikulska A, Gluchowska KM, Szostakowska-Rodzos M, Zagozdzon A, Bausbacher T, Tkaczyk A, Kulma M, Pomper P, Mlacki M, Jagielski AK, Blaszczyk R, Hopf C, and Zaslona Z. Sci Rep. 2025. 15(1):18741.
    DOI: 10.1038/s41598-025-03446-1.
15. Central projections of nociceptive input originating from the low back and limb muscle in rats.
    Hoheisel U, Treede RD, Mense S, and Taguchi T. Sci Rep. 2025. 15(1):2552.
    DOI: 10.1038/s41598-025-86832-z.
16. Differentiating Glioma Recurrence and Pseudoprogression by APTw CEST MRI.
    Karimian-Jazi K, Enbergs N, Golubtsov E, Schregel K, Ungermann J, Fels-Palesandro H, Schwarz D, Sturm V, Kernbach JM, Batra D, Ippen FM, Pfluger I, von Knebel Doeberitz N, Heiland S, Bunse L, Platten M, Winkler F, Wick W, Paech D, Bendszus M, and Breckwoldt MO. Invest Radiol. 2025. 60(6):414-422.
    DOI: 10.1097/RLI.0000000000001145.
17. The Rise of Stereotactic Neurosurgery in Germany.
    Kinfe TM, Coenen VA, and Krauss JK. J Neurol Surg A Cent Eur Neurosurg. 2025. 86(S 01):S15-S22.
    DOI: 10.1055/a-2558-3307.
18. Multiple Sclerosis: Glial Cell Diversity in Time and Space.
    Kooistra SM and Schirmer L. Glia. 2025. 73(3):574-590.
    DOI: 10.1002/glia.24655.
19. Utilization of universal-targeting mSA2 CAR-T cells for the treatment of glioblastoma.
    Kourtesakis A, Bailey E, Chow HNH, Rohdjess H, Mussnig N, Agardy DA, Hoffmann DCF, Chih YC, Will R, Kaulen L, Hahn M, Wagener R, Reibold D, Pusch S, Sahm F, Sauer T, Schmitt M, Bunse L, Platten M, Wick W, and Kessler T. Oncoimmunology. 2025. 14(1):2518631.
    DOI: 10.1080/2162402X.2025.2518631.
20. Intertwined destinies - Acute ischemic stroke and neurogenic stress cardiomyopathy.
    Kruska M, Alonso A, Akin I, and Fastner C. J Stroke Cerebrovasc Dis. 2025:108222.
    DOI: 10.1016/j.jstrokecerebrovasdis.2024.108222.
21. Strength, extent and duration of secondary hyperalgesia induced by high-frequency electrical stimulation of the foot compared to the volar forearm of healthy human volunteers.
    Lebrun L, Lenoir C, Leone C, van den Broeke EN, Caspani O, Schilder A, Pelz B, Truini A, Treede RD, and Mouraux A. PLoS One. 2025. 20(2):e0318934.
    DOI: 10.1371/journal.pone.0318934.
22. Repeated exposure to cutaneous high-frequency electrical stimulation prolongs the time course of secondary hyperalgesia.
    Lebrun L, Stouffs A, Hermans E, van den Broeke EN, Leone C, Caspani O, Truini A, Garcia-Larrea L, Treede RD, and Mouraux A. J Neurophysiol. 2025. 133(6):1933-1946.
    DOI: 10.1152/jn.00130.2025.
23. Myocardial injury in spontaneous intracerebral hemorrhage is not predicted by prior cardiac disease or neurological status: results from the Mannheim Stroke database.
    Lesch H, Haucke L, Kruska M, Ebert A, Becker L, Szabo K, Akin I, Alonso A, and Fastner C. Front Neurol. 2025. 16:1510361.
    DOI: 10.3389/fneur.2025.1510361.
24. Provision, cough efficacy and treatment satisfaction of mechanical insufflation-exsufflation in a large multicenter cohort of patients with amyotrophic lateral sclerosis.
    Maier A, Kettemann D, Weyen U, Grehl T, Schulte PC, Steinbach R, Rodiger A, Weydt P, Petri S, Wolf J, Grosskreutz J, Koch JC, Weishaupt JH, Rosseau S, Norden J, Kortvelyessy P, Koch B, Holm T, Hildebrandt B, Schumann P, Walter B, Riitano A, Munch C, Meyer T, and Spittel S. Sci Rep. 2025. 15(1):7360.
    DOI: 10.1038/s41598-025-91692-8.
25. SOD1 gene screening in ALS - frequency of mutations, patients' attitudes to genetic information and transition to tofersen treatment in a multi-center program.
    Meyer T, Schumann P, Grehl T, Weyen U, Petri S, Rodiger A, Steinbach R, Grosskreutz J, Bernsen S, Weydt P, Wolf J, Gunther R, Vidovic M, Baum P, Metelmann M, Weishaupt JH, Streubel B, Kasper DC, Koc Y, Kettemann D, Norden J, Schmitt P, Walter B, Munch C, Spittel S, Maier A, and Kortvelyessy P. Amyotroph Lateral Scler Frontotemporal Degener. 2025. 26(1-2):162-171.
    DOI: 10.1080/21678421.2024.2401131.
26. Shared prognostic information in amyotrophic lateral sclerosis - systematic assessment of the patients' perception of neurofilament light chain and the ALS functional rating scale.
    Mohwald LM, Maier A, Grehl T, Weyen U, Weydt P, Gunther R, Lingor P, Goricke B, Petri S, Grosskreutz J, Boentert M, Cordts I, Weishaupt JH, Dorst J, Munch C, Meyer T, and Baum P. Neurol Res Pract. 2025. 7(1):6.
    DOI: 10.1186/s42466-024-00363-y.
27. Association of the Cervical Canal Area With Disability and Progression in People With Multiple Sclerosis.
    Mongay-Ochoa N, Pareto D, Alberich M, Carbonell-Mirabent P, Valsasina P, Margoni M, Braga N, Vidal-Jordana A, Auger C, Tintore M, Meani A, Gobbi C, Zecca C, Barkhof F, Schoonheim MM, Strijbis EMM, Gallo A, Bisecco A, Ciccarelli O, De Angelis F, Yiannakas MC, Palace J, Matthews L, Gass A, Eisele P, Lukas C, Bellenberg B, Preziosa P, Montalban X, Rocca MA, Filippi M, Rovira A, Sastre-Garriga J, and group Ms. Neurology. 2025. 104(1):e210136.
    DOI: 10.1212/WNL.0000000000210136.
28. Exploring the Abeta Plaque Microenvironment in Alzheimer's Disease Model Mice by Multimodal Lipid-Protein-Histology Imaging on a Benchtop Mass Spectrometer.
    Muller E, Enzlein T, Niemeyer D, von Ammon L, Stumpo K, Biber K, Klein C, and Hopf C. Pharmaceuticals (Basel). 2025. 18(2).
    DOI: 10.3390/ph18020252.
29. An inflammation-associated lncRNA induces neuronal damage via mitochondrial dysfunction.
    Olazagoitia-Garmendia A, Rojas-Marquez H, Trobisch T, Moreno-Castro C, Rodriguez Etxebarria A, Mentxaka J, Tripathi A, Yang B, Martin Ruiz I, Anguita J, Meana JJ, Ding Y, Dutta R, Schirmer L, Igoillo-Esteve M, Santin I, and Castellanos-Rubio A. Mol Ther Nucleic Acids. 2025. 36(2):102533.
    DOI: 10.1016/j.omtn.2025.102533.
30. Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy.
    Peng T, Ma X, Hua W, Wang C, Chu Y, Sun M, Fermi V, Hamelmann S, Lindner K, Shao C, Zaman J, Tian W, Zhuo Y, Harim Y, Stoffler N, Hammann L, Xiao Q, Jin X, Warta R, Lotsch C, Zhuang X, Feng Y, Fu M, Zhang X, Zhang J, Xu H, Qiu F, Xie L, Zhang Y, Zhu W, Du Z, Salgueiro L, Schneider M, Eichhorn F, Lefevre A, Pusch S, Grinevich V, Ratliff M, Loges S, Bunse L, Sahm F, Xiang Y, Unterberg A, von Deimling A, Platten M, Herold-Mende C, Wu Y, Liu HK, and Mao Y. Cell Stem Cell. 2025. 32(4):652-669 e11.
    DOI: 10.1016/j.stem.2025.01.002.
31. Antiplatelet Use Prior to Anticoagulant Initiation in Patients With Atrial Fibrillation-Related Ischemic Stroke: An ELAN Trial Analysis.
    Polymeris AA, Koga M, Strbian D, Vedamurthy A, Krishnan M, Branca M, Horvath T, Goeldlin M, Shim G, Gumbinger C, Zhang L, Kristoffersen ES, Desfontaines P, Vanacker P, Alonso A, Poli S, Nunes AP, Caracciolo NG, Kneihsl M, Kahles T, Giudici D, Raty S, Tiainen M, Dawson J, Fischer U, and Investigators E. J Stroke. 2025. 27(2):217-227.
    DOI: 10.5853/jos.2024.04322.
32. Hippocampal contributions to semantic memory retrieval: Strategy-specific impairments in transient global amnesia.
    Sandikci V, Ebert A, Marzina A, Platten M, Szabo K, and Hoyer C. J Neuropsychol. 2025.
    DOI: 10.1111/jnp.12430.
33. Tailoring anaesthetic strategies for diabetes research: Acepromazine vs. medetomidine in Aachen minipigs.
    Soares S, Wuhl E, Schlund A, Schneider T, Sohns K, Rukwied R, Schmelz M, and Kranzlin B. PLoS One. 2025. 20(1):e0316570.
    DOI: 10.1371/journal.pone.0316570.
34. Self-assessment of amyotrophic lateral sclerosis functional rating scale on the patient's smartphone proves to be non-inferior to clinic data capture.
    Steinfurth L, Grehl T, Weyen U, Kettemann D, Steinbach R, Rodiger A, Grosskreutz J, Petri S, Boentert M, Weydt P, Bernsen S, Walter B, Gu NR, Lingor P, Koch JC, Baum P, Weishaupt JH, Dorst J, Koc Y, Cordts I, Vidovic M, Norden J, Schumann P, Kortvelyessy P, Spittel S, Munch C, Maier A, and Meyer T. Amyotroph Lateral Scler Frontotemporal Degener. 2025:1-12.
    DOI: 10.1080/21678421.2025.2468404.
35. Treatment of glioblastoma patients with personalized vaccines outside clinical trials: Lessons ignored?Tabatabai G, Platten M, Preusser M, Weller M, Wick W, and van den Bent M. Neuro Oncol. 2025. 27(1):302-305.
    DOI: 10.1093/neuonc/noae225.
36. Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy.
    Tan CL, Lindner K, Boschert T, Meng Z, Rodriguez Ehrenfried A, De Roia A, Haltenhof G, Faenza A, Imperatore F, Bunse L, Lindner JM, Harbottle RP, Ratliff M, Offringa R, Poschke I, Platten M, and Green EW. Nat Biotechnol. 2025. 43(1):134-142.
    DOI: 10.1038/s41587-024-02161-y.
37. Disease-State Dependent Associations Between Intrinsic Brain Function and Symptoms of Fatigue, Depression, and Anxiety in Crohn's Disease.
    Thomann AK, Schmitgen MM, Stephan JC, Knoedler LL, Gass A, Thomann PA, Ebert MP, Reindl W, and Wolf RC. Inflamm Bowel Dis. 2025.
    DOI: 10.1093/ibd/izae318.
38. Live imaging of excitable axonal microdomains in ankyrin-G-GFP mice.
    Thome C, Janssen JM, Karabulut S, Acuna C, D'Este E, Soyka SJ, Baum K, Bock M, Lehmann N, Roos J, Stevens NA, Hasegawa M, Ganea DA, Benoit CM, Grundemann J, Min LY, Bird KM, Schultz C, Bennett V, Jenkins PM, and Engelhardt M. Elife. 2025. 12.
    DOI: 10.7554/eLife.87078.
39. How to classify patients suffering from chronic pain associated with infectious diseases.
    Treede RD. Pain. 2025.
    DOI: 10.1097/j.pain.0000000000003644.
40. Slow depolarizing electrical stimuli reveal differential time courses of nociceptor recovery after prolonged topical capsaicin in human skin.
    Tumbala Gutti D, Carr R, Schmelz M, and Rukwied R. Eur J Pain. 2025. 29(2):e4726.
    DOI: 10.1002/ejp.4726.
41. Systematic Review and Meta-Analysis: The Association Between Newer-Generation Antidepressants and Insomnia in Children and Adolescents With Major Depressive Disorder.
    Turkmen C, Machunze N, Lee AM, Bougelet E, Ludin NM, de Cates AN, Vollstadt-Klein S, Bach P, Kiefer F, Andreas JB, Kamphuis J, Schoevers RA, Emslie GJ, Hetrick SE, Viechtbauer W, and van Dalfsen JH. J Am Acad Child Adolesc Psychiatry. 2025.
    DOI: 10.1016/j.jaac.2025.01.006.
42. Glucose intake reduces alcohol craving and amplifies habituation to cue-induced brain activation in male patients with alcohol use disorder: A randomized, placebo-controlled crossover study examining male and female patients with AUD.
    Wetzel L, Hoffmann S, Reinhard I, Riegler A, Pourbaix M, Ardern I, Link T, Vollstadt-Klein S, Lenz B, Kiefer F, Bach P, and Koopmann A. Psychoneuroendocrinology. 2025. 177:107456.
    DOI: 10.1016/j.psyneuen.2025.107456.
43. Emerging mechanisms and therapeutics in inflammatory muscle diseases.
    Wischnewski S, Rausch HW, Ikenaga C, Leipe J, Lloyd TE, and Schirmer L. Trends Pharmacol Sci. 2025. 46(3):249-263.
    DOI: 10.1016/j.tips.2025.01.005.