Publications with MCTN Affiliation 2024

Stress-Induced Sensitization of Insula Activation Predicts Alcohol Craving and Alcohol Use in Alcohol Use Disorder.
Bach P, Zaiser J, Zimmermann S, Gessner T, Hoffmann S, Gerhardt S, Berhe O, Bekier NK, Abel M, Radler P, Langejurgen J, Tost H, Lenz B, Vollstadt-Klein S, Stallkamp J, Kirschbaum C, and Kiefer F. Biol Psychiatry. 2024. 95(3):245-255.
DOI: 10.1016/j.biopsych.2023.08.024. 

[Acute ischemic stroke and troponin elevation: update of the Mannheim clinical algorithm].
Becker L, Alonso A, Kruska M, Baumann S, Grassl N, Lesch H, Eisele P, Sieburg T, Behnes M, Schupp T, Kayed H, Platten M, Duerschmied D, Szabo K, Akin I, and Fastner C. Inn Med (Heidelb). 2024.
DOI: 10.1007/s00108-024-01719-x.

H3K27M neoepitope vaccination in diffuse midline glioma induces B and T cell responses across diverse HLA loci of a recovered patient.
Boschert T, Kromer K, Lerner T, Lindner K, Haltenhof G, Tan CL, Jahne K, Poschke I, Bunse L, Eisele P, Grassl N, Mildenberger I, Sahm K, Platten M, Lindner JM, and Green EW. Sci Adv. 2024. 10(5):eadi9091.
DOI: 10.1126/sciadv.adi9091. 

A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice.
Brenner D, Sieverding K, Srinidhi J, Zellner S, Secker C, Yilmaz R, Dyckow J, Amr S, Ponomarenko A, Tunaboylu E, Douahem Y, Schlag JS, Rodriguez Martinez L, Kislinger G, Niemann C, Nalbach K, Ruf WP, Uhl J, Hollenbeck J, Schirmer L, Catanese A, Lobsiger CS, Danzer KM, Yilmazer-Hanke D, Munch C, Koch P, Freischmidt A, Fetting M, Behrends C, Parlato R, and Weishaupt JH. J Exp Med. 2024. 221(5).
DOI: 10.1084/jem.20221190. 

T-FINDER: A highly sensitive, pan-HLA platform for functional T cell receptor and ligand discovery.
Cetin M, Pinamonti V, Schmid T, Boschert T, Mellado Fuentes A, Kromer K, Lerner T, Zhang J, Herzig Y, Ehlert C, Hernandez-Hernandez M, Samaras G, Torres CM, Fisch L, Dragan V, Kouwenhoven A, Van Schoubroeck B, Wils H, Van Hove C, Platten M, Green EW, Stevenaert F, Felix NJ, and Lindner JM. Sci Adv. 2024. 10(5):eadk3060.
DOI: 10.1126/sciadv.adk3060. 

Systematic review and co-ordinate based meta-analysis to summarize the utilization of functional brain imaging in conjunction with human models of peripheral and central sensitization.
Clarke S, Rogers R, Wanigasekera V, Fardo F, Pia H, Nochi Z, Macian N, Leray V, Finnerup NB, Pickering G, Mouraux A, Truini A, Treede RD, Garcia-Larrea L, and Tracey I. Eur J Pain. 2024.
DOI: 10.1002/ejp.2251. 

An integrative miRNA-mRNA expression analysis identifies miRNA signatures associated with SOD1 and TARDBP patient-derived motor neurons.
Dash BP, Freischmidt A, Weishaupt JH, and Hermann A. Hum Mol Genet. 2024.
DOI: 10.1093/hmg/ddae072. 

Measuring interpersonal trauma: Development and validation of the German version of the victimization experience schedule (VES).
Drusko A, Renz M, Schmidt H, Rosin M, Simon J, Beiner E, Charalambides M, Meyer-Lindenberg A, Treede RD, Tost H, and Tesarz J. J Psychosom Res. 2024. 179:111626.
DOI: 10.1016/j.jpsychores.2024.111626. 

Integrative Single-Plaque Analysis Reveals Signature Abeta and Lipid Profiles in the Alzheimer's Brain.
Enzlein T, Lashley T, Sammour DA, Hopf C, and Chavez-Gutierrez L. Anal Chem. 2024.
DOI: 10.1021/acs.analchem.3c05557. 

Cue-exposure treatment influences resting-state functional connectivity-a randomized controlled fMRI study in alcohol use disorder.
Farre-Colomes A, Tan H, Gerhardt S, Gerchen MF, Kirsch M, Hoffmann S, Kirsch P, Kiefer F, and Vollstadt-Klein S. Psychopharmacology (Berl). 2024.
DOI: 10.1007/s00213-024-06531-x. 

Cell-cell contacts prevent t-BuOOH-triggered ferroptosis and cellular damage in vitro by regulation of intracellular calcium.
Faust D, Wenz C, Holm S, Harms G, Greffrath W, and Dietrich C. Arch Toxicol. 2024.
DOI: 10.1007/s00204-024-03792-5. 

Placebo and nocebo responses in painful diabetic neuropathy: systematic review and meta-analysis.
Frisaldi E, Vollert J, Al Sultani H, Benedetti F, and Shaibani A. Pain. 2024. 165(1):29-43.
DOI: 10.1097/j.pain.0000000000003000. 

L-RNA aptamer-based CXCL12 inhibition combined with radiotherapy in newly-diagnosed glioblastoma: dose escalation of the phase I/II GLORIA trial.
Giordano FA, Layer JP, Leonardelli S, Friker LL, Turiello R, Corvino D, Zeyen T, Schaub C, Muller W, Sperk E, Schmeel LC, Sahm K, Oster C, Kebir S, Hambsch P, Pietsch T, Bisdas S, Platten M, Glas M, Seidel C, Herrlinger U, and Holzel M. Nat Commun. 2024. 15(1):4210.
DOI: 10.1038/s41467-024-48416-9. 

Patient engagement in designing, conducting, and disseminating clinical pain research: IMMPACT recommended considerations.
Haroutounian S, Holzer KJ, Kerns RD, Veasley C, Dworkin RH, Turk DC, Carman KL, Chambers CT, Cowan P, Edwards RR, Eisenach JC, Farrar JT, Ferguson M, Forsythe LP, Freeman R, Gewandter JS, Gilron I, Goertz C, Grol-Prokopczyk H, Iyengar S, Jordan I, Kamp C, Kleykamp BA, Knowles RL, Langford DJ, Mackey S, Malamut R, Markman J, Martin KR, McNicol E, Patel KV, Rice ASC, Rowbotham M, Sandbrink F, Simon LS, Steiner DJ, and Vollert J. Pain. 2024. 165(5):1013-1028.
DOI: 10.1097/j.pain.0000000000003121. 

GABAergic interneuron diversity and organization are crucial for the generation of human-specific functional neural networks in cerebral organoids.
Heesen SH and Kohr G. Front Cell Neurosci. 2024. 18:1389335.
DOI: 10.3389/fncel.2024.1389335. 

PerSurge (NOA-30) phase II trial of perampanel treatment around surgery in patients with progressive glioblastoma.
Heuer S, Burghaus I, Gose M, Kessler T, Sahm F, Vollmuth P, Venkataramani V, Hoffmann D, Schlesner M, Ratliff M, Hopf C, Herrlinger U, Ricklefs F, Bendszus M, Krieg SM, Wick A, Wick W, and Winkler F. BMC Cancer. 2024. 24(1):135.
DOI: 10.1186/s12885-024-11846-1. 

Associations of Menstrual Cycle and Progesterone-to-Estradiol Ratio With Alcohol Consumption in Alcohol Use Disorder: A Sex-Separated Multicenter Longitudinal Study.
Hoffmann S, Gerhardt S, Muhle C, Reinhard I, Reichert D, Bach P, Boroumand-Jazi R, Kuehner C, Aguilera A, Aslan A, Bahr NS, Belanger M, Deeken F, Ebrahimi C, Fischbach PC, Ganz M, Garbusow M, Grosskopf CM, Heigert M, Hentschel A, Karl D, Liu S, Mazza M, Pelz P, Pinger M, Reichl M, Riemerschmid C, Rosenthal A, Steffen J, Strehle J, Wedemeyer F, Weiss F, Wenzel J, Wieder G, Wieland A, Zaiser J, Zech HG, Zimmermann S, Kornhuber J, Muller CP, Sommer WH, Spanagel R, Banaschewski T, Deserno L, Ebner-Priemer UW, Flor H, Kirsch P, Rietschel M, Vollstadt-Klein S, Walter H, Meyer-Lindenberg A, Rapp MA, Witt S, Smolka MN, Heinz A, Tost H, Kiefer F, Reichert M, Lenz B, and ReCoDe C. Am J Psychiatry. 2024:appiajp20230027.
DOI: 10.1176/appi.ajp.20230027. 

Placebo analgesia in physical and psychological interventions: Systematic review and meta-analysis of three-armed trials.
Hohenschurz-Schmidt D, Phalip J, Chan J, Gauhe G, Soliman N, Vollert J, Lunde SJ, and Vase L. Eur J Pain. 2024. 28(4):513-531.
DOI: 10.1002/ejp.2205. 

Schwann cells in neuromuscular in vitro models.
Horner SJ, Couturier N, Hafner M, and Rudolf R. Biol Chem. 2024. 405(1):25-30.
DOI: 10.1515/hsz-2023-0172. 

Identification of galectin-3 as a novel potential prognostic/predictive biomarker and therapeutic target for cerebral cavernous malformation disease.
Kar S, Perrelli A, Bali KK, Mastrocola R, Kar A, Khan B, Gand L, Nayak A, Hartmann C, Kunz WS, Samii A, Bertalanffy H, and Retta SF. Genes Dis. 2024. 11(1):67-71.
DOI: 10.1016/j.gendis.2023.02.045.

The immunoglobulin superfamily ligand B7H6 subjects T cell responses to NK cell surveillance.
Kilian M, Friedrich MJ, Lu KH, Vonhoren D, Jansky S, Michel J, Keib A, Stange S, Hackert N, Kehl N, Hahn M, Habel A, Jung S, Jahne K, Sahm F, Betge J, Cerwenka A, Westermann F, Dreger P, Raab MS, Meindl-Beinker NM, Ebert M, Bunse L, Muller-Tidow C, Schmitt M, and Platten M. Sci Immunol. 2024. 9(95):eadj7970.
DOI: 10.1126/sciimmunol.adj7970. 

Oxaliplatin-induced Acute Neurotoxicity Recovers Between Repeat Infusion Cycles: An Axonal Excitability Repeated Multiple Measurements Study.
Kokotis P, Papantoniou M, Carr RW, Schmelz M, Siakavella D, Skafida E, and Papadimitriou C. Cancer Diagn Progn. 2024. 4(3):320-325.
DOI: 10.21873/cdp.10327. 

Patients' perspective on the chronic pain classification in the 11th revision of the International Classification of Diseases (ICD-11): results from an international web-based survey.
Korwisi B, Hay G, Forget P, Ryan D, Treede RD, Rief W, and Barke A. Pain. 2024.
DOI: 10.1097/j.pain.0000000000003248. 

NLGN4X TCR transgenic T cells to treat gliomas.
Kramer C, Kilian M, Chih YC, Kourtesakis A, Hoffmann DC, Boschert T, Koopmann P, Sanghvi K, De Roia A, Jung S, Jahne K, Day B, Shultz LD, Ratliff M, Harbottle R, Green EW, Will R, Wick W, Platten M, and Bunse L. Neuro Oncol. 2024. 26(2):266-278.
DOI: 10.1093/neuonc/noad172. 

The peroxisome: an update on mysteries 3.0.
Kumar R, Islinger M, Worthy H, Carmichael R, and Schrader M. Histochem Cell Biol. 2024.
DOI: 10.1007/s00418-023-02259-5. 

Neural deception: Breast cancer co-opts neuronal mechanisms to evade the immune system.
Layer N, Bunse L, and Venkataramani V. Cancer Cell. 2024.
DOI: 10.1016/j.ccell.2024.05.007. 

Clinical Features and Voxel-Based-Symptom-Lesion Mapping of Silent Aspiration in Acute Infratentorial Stroke.
Lesch H, Wittayer M, Dias M, Nick A, Ebert A, Eisele P, and Alonso A. Dysphagia. 2024. 39(2):289-298.
DOI: 10.1007/s00455-023-10611-z. 

Intra-arterial delivery of neurospheres into isolated perfused porcine colons: a proof of concept.
Martel RD, Hoyos NA, Tapia-Laliena MA, Herrmann I, Herrmann M, Khasanov R, and Schafer KH. Biol Methods Protoc. 2024. 9(1):bpae022.
DOI: 10.1093/biomethods/bpae022. 

Interindividual variability in cold-pressor pain sensitivity is not explained by peripheral vascular responding and generalizes to a C-nociceptor-specific pain phenotype.
Martel RD, Papafragou G, Weigand S, Rolke R, Prawitt D, Birklein F, Treede RD, and Magerl W. Pain. 2024.
DOI: 10.1097/j.pain.0000000000003049. 

MediMer: a versatile do-it-yourself peptide-receptive MHC class I multimer platform for tumor neoantigen-specific T cell detection.
Meyer M, Parpoulas C, Barthelemy T, Becker JP, Charoentong P, Lyu Y, Borsig S, Bulbuc N, Tessmer C, Weinacht L, Ibberson D, Schmidt P, Pipkorn R, Eichmuller SB, Steinberger P, Lindner K, Poschke I, Platten M, Frohling S, Riemer AB, Hassel JC, Roberti MP, Jager D, Zornig I, and Momburg F. Front Immunol. 2023. 14:1294565.
DOI: 10.3389/fimmu.2023.1294565. 

New ICD-11 diagnostic criteria for chronic secondary musculoskeletal pain associated with Parkinson disease.
Mylius V, Moisset X, Rukavina K, Rosner J, Korwisi B, Marques A, Lloret SP, Kagi G, Bohlhalter S, Bannister K, Chaudhuri KR, Barke A, Tinazzi M, Brefel-Courbon C, Treede RD, and de Andrade DC. Pain. 2024.
DOI: 10.1097/j.pain.0000000000003138. 

Type 1 Myocardial Infarction in Patients With Acute Ischemic Stroke.
Nolte CH, von Rennenberg R, Litmeier S, Leistner DM, Szabo K, Baumann S, Mengel A, Michalski D, Siepmann T, Blankenberg S, Petzold GC, Dichgans M, Katus H, Pieske B, Regitz-Zagrosek V, Braemswig TB, Rangus I, Pepic A, Vettorazzi E, Zeiher AM, Scheitz JF, Wegscheider K, Landmesser U, and Endres M. JAMA Neurol. 2024.
DOI: 10.1001/jamaneurol.2024.1552. 

Celebrating the 30th Anniversary of the European Association of Neuro-Oncology (EANO).
Preusser M, Platten M, and Short SC. Neuro Oncol. 2024.
DOI: 10.1093/neuonc/noae039. 

A generalizable deep voxel-guided morphometry algorithm for the detection of subtle lesion dynamics in multiple sclerosis.
Raj A, Gass A, Eisele P, Dabringhaus A, Kraemer M, and Zollner FG. Front Neurosci. 2024. 18:1326108.
DOI: 10.3389/fnins.2024.1326108. 

Deep-learning-based reconstruction of undersampled MRI to reduce scan times: a multicentre, retrospective, cohort study.
Rastogi A, Brugnara G, Foltyn-Dumitru M, Mahmutoglu MA, Preetha CJ, Kobler E, Pfluger I, Schell M, Deike-Hofmann K, Kessler T, van den Bent MJ, Idbaih A, Platten M, Brandes AA, Nabors B, Stupp R, Bernhardt D, Debus J, Abdollahi A, Gorlia T, Tonn JC, Weller M, Maier-Hein KH, Radbruch A, Wick W, Bendszus M, Meredig H, Kurz FT, and Vollmuth P. Lancet Oncol. 2024. 25(3):400-410.
DOI: 10.1016/S1470-2045(23)00641-1. 

Myosin Va: Capturing cAMP for synaptic plasticity.
Rudolf R. Front Physiol. 2023. 14:1342994.
DOI: 10.3389/fphys.2023.1342994. 

Sympathetic innervation in skeletal muscle and its role at the neuromuscular junction.
Rudolf R, Kettelhut IC, and Navegantes LCC. J Muscle Res Cell Motil. 2024.
DOI: 10.1007/s10974-024-09665-9. 

[Immunotherapy against gliomas].
Sahm K and Weiss T. Nervenarzt. 2024.
DOI: 10.1007/s00115-023-01590-5. 

In-depth analysis of data from the RAS-ALS study reveals new insights in rasagiline treatment for amyotrophic lateral sclerosis.
Schuster J, Dreyhaupt J, Monkemoller K, Dupuis L, Dieterle S, Weishaupt JH, Kassubek J, Petri S, Meyer T, Grosskreutz J, Schrank B, Boentert M, Emmer A, Hermann A, Zeller D, Prudlo J, Winkler AS, Grehl T, Heneka MT, Johannesen S, Goricke B, Witzel S, Dorst J, Ludolph AC, and Group R-AS. Eur J Neurol. 2024:e16204.
DOI: 10.1111/ene.16204. 

Electrical matrix stimulation suppresses acute itch independently of activation of sleeping nociceptors.
Schwarzenauer M, Rukwied RM, Lampert A, Rolke R, and Namer B. Eur J Pain. 2024. 28(2):285-296.
DOI: 10.1002/ejp.2177. 

Analysis of the Mouse Hepatic Peroxisome Proteome-Identification of Novel Protein Constituents Using a Semi-Quantitative SWATH-MS Approach.
Singin O, Astapenka A, Costina V, Kuhl S, Bonekamp N, Drews O, and Islinger M. Cells. 2024. 13(2).
DOI: 10.3390/cells13020176. 

Skin Innervation.
Stander S and Schmelz M. J Invest Dermatol. 2024.
DOI: 10.1016/j.jid.2023.10.047. 

Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy.
Tan CL, Lindner K, Boschert T, Meng Z, Rodriguez Ehrenfried A, De Roia A, Haltenhof G, Faenza A, Imperatore F, Bunse L, Lindner JM, Harbottle RP, Ratliff M, Offringa R, Poschke I, Platten M, and Green EW. Nat Biotechnol. 2024.
DOI: 10.1038/s41587-024-02161-y. 

High-Throughput Miniaturized Synthesis of PROTAC-Like Molecules.
Tian Y, Seifermann M, Bauer L, Luchena C, Wiedmann JJ, Schmidt S, Geisel A, Afonin S, Hopfner J, Brehm M, Liu X, Hopf C, Popova AA, and Levkin PA. Small. 2024:e2307215.
DOI: 10.1002/smll.202307215. 

Interactions between 2 subtypes of central sensitization in rats and humans: spinal long-term potentiation and brainstem controls.
Treede RD. Pain. 2024.
DOI: 10.1097/j.pain.0000000000003167. 

Sports participation moderates the risk of family-specific negative life events on alcohol use among adolescents: Evidence from the longitudinal MyLife study.
Turkmen C, Brunborg GS, Lund IO, Kiefer F, Vollstadt-Klein S, and Burdzovic Andreas J. Addict Behav. 2024. 155:108041.
DOI: 10.1016/j.addbeh.2024.108041. 

Paradoxical heat sensation as a manifestation of thermal hypesthesia: a study of 1090 patients with lesions of the somatosensory system.
Vollert J, Fardo F, Attal N, Baron R, Bouhassira D, Enax-Krumova EK, Freynhagen R, Hansson P, Jensen TS, Kersebaum D, Maier C, Pogatzki-Zahn E, Rice ASC, Sachau J, Schaldemose EL, Segerdahl M, Sendel M, Tolle TR, Finnerup NB, and Treede RD. Pain. 2024. 165(1):216-224.
DOI: 10.1097/j.pain.0000000000003014. 

TRPV1 Channel in Human Eosinophils: Functional Expression and Inflammatory Modulation.
Weihrauch T, Gray N, Wiebe D, Schmelz M, Limberg MM, and Raap U. Int J Mol Sci. 2024. 25(3).
DOI: 10.3390/ijms25031922. 

A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits.
Wietek J, Nozownik A, Pulin M, Saraf-Sinik I, Matosevich N, Gowrishankar R, Gat A, Malan D, Brown BJ, Dine J, Imambocus BN, Levy R, Sauter K, Litvin A, Regev N, Subramaniam S, Abrera K, Summarli D, Goren EM, Mizrachi G, Bitton E, Benjamin A, Copits BA, Sasse P, Rost BR, Schmitz D, Bruchas MR, Soba P, Oren-Suissa M, Nir Y, Wiegert JS, and Yizhar O. Nat Methods. 2024.
DOI: 10.1038/s41592-024-02285-8. 

Cell type mapping of inflammatory muscle diseases highlights selective myofiber vulnerability in inclusion body myositis.
Wischnewski S, Thawel T, Ikenaga C, Kocharyan A, Lerma-Martin C, Zulji A, Rausch HW, Brenner D, Thomas L, Kutza M, Wick B, Trobisch T, Preusse C, Haeussler M, Leipe J, Ludolph A, Rosenbohm A, Hoke A, Platten M, Weishaupt JH, Sommer CJ, Stenzel W, Lloyd TE, and Schirmer L. Nat Aging. 2024.
DOI: 10.1038/s43587-024-00645-9. 

Alzheimer's disease linked Abeta42 exerts product feedback inhibition on gamma-secretase impairing downstream cell signaling.
Zoltowska KM, Das U, Lismont S, Enzlein T, Maesako M, Houser MC, Franco ML, Ozcan B, Moreira DG, Karachentsev D, Becker A, Hopf C, Vilar M, Berezovska O, Mobley W, and Chavez-Gutierrez L. bioRxiv. 2024.
DOI: 10.1101/2023.08.02.551596.