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MI3 PUBLICATIONS

2021

Nascent Ribo-Seq measures ribosomal loading time and reveals kinetic impact on ribosome density. Schott J, Reitter S, Lindner D, Grosser J, Bruer M, Shenoy A, Geiger T, Mathes A, Dobreva G, Stoecklin G.  Nat Methods. 2021 Sep 3. doi: 10.1038/s41592-021-01250-z. Epub ahead of print. PMID: 34480152.

Patient and Graft Survival After Dual Kidney Transplantation With Marginal Donors in Comparison to Matched Control Groups. Yazdani B, Marinez J, Krüger B, Kälsch AI, Jung M, Chen G, Leipe J, Benck U, Schnülle P, Nuhn P, Keese M, Schwenke K, Krämer BK. Transplant Proc. 2021 Aug 21:S0041-1345(21)00490-5. doi: 10.1016/j.transproceed.2021.07.016. Online ahead of print.

PPARγ induces PD-L1 expression in MSS+ colorectal cancer cells. Gutting T, Hauber V, Pahl J, Klapproth K, Wu W, Dobrota I, Herweck F, Reichling J, Helm L, Schroeder T, Li B, Weidner P, Zhan T, Eckardt M, Betge J, Belle S, Sticht C, Gaiser T, Boutros M, Ebert MPA, Cerwenka A, Burgermeister E. Oncoimmunology. 2021 May 5;10(1):1906500. doi: 10.1080/2162402X.2021.1906500. PMID: 34026331

Regulation of Expression of the TIR-Containing Protein CGene of the Uropathogenic Escherichia coliStrain CFT073. Ittensohn J, Hemberger J, Griffiths H, Keller M, Albrecht S, Miethke T. Pathogens. 2021 May 1;10(5):549. doi: 10.3390/pathogens10050549. PMID: 34062817; PMCID: PMC8147327.

C-terminal and intact FGF23 in kidney transplant recipients and their associations with overall graft survival. Chu C, Elitok S, Zeng S, Xiong Y, Hocher CF, Hasan AA, Krämer BK, Hocher B. BMC Nephrol. 2021 Apr 8;22(1):125. doi: 10.1186/s12882-021-02329-7.

STAT3 governs the HIF-1α response in IL-15 primed human NK cells. Coulibaly A, Velásquez SY, Kassner N, Schulte J, Barbarossa MV, Lindner HA. Sci Rep. 2021 Mar 29;11(1):7023. doi: 10.1038/s41598-021-84916-0. PMID: 33782423.

A vaccine targeting mutant IDH1 in newly diagnosed glioma. Platten M, Bunse L, Wick A, Bunse T, Le Cornet L, Harting I, Sahm F, Sanghvi K, Tan CL, Poschke I, Green E, Justesen S, Behrens GA, Breckwoldt MO, Freitag A, Rother LM, Schmitt A, Schnell O, Hense J, Misch M, Krex D, Stevanovic S, Tabatabai G, Steinbach JP, Bendszus M, von Deimling A, Schmitt M, Wick W. Nature. 2021 Apr;592(7854):463-468. doi: 10.1038/s41586-021-03363-z. Epub 2021 Mar 24. PMID: 33762734; PMCID: PMC8046668.

A Comparative Transcriptome Analysis of Human and Porcine Choroid Plexus Cells in Response to Streptococcus suis Serotype 2 Infection Points to a Role of Hypoxia. Lauer AN, Scholtysik R, Beineke A, Baums CG, Klose K, Valentin-Weigand P, Ishikawa H, Schroten H, Klein-Hitpass L, Schwerk C. Front Cell Infect Microbiol. 2021 Mar 8;11:639620. doi: 10.3389/fcimb.2021.639620. PMID: 33763387; PMCID: PMC7982935.

Lung Protection vs. Infection Resolution: Interleukin 10 Suspected of Double-Dealing in COVID-19. Lindner HA, Velásquez SY, Thiel M, Kirschning T. Front Immunol. 2021 Mar 3;12:602130. doi: 10.3389/fimmu.2021.602130. PMID: 33746948; PMCID: PMC7966717.

Blocking Migration of Polymorphonuclear Myeloid-Derived Suppressor Cells Inhibits Mouse Melanoma Progression. Groth C, Arpinati L, Shaul ME, Winkler N, Diester K, Gengenbacher N, Weber R, Arkhypov I, Lasser S, Petrova V, Augustin HG, Altevogt P, Utikal J, Fridlender ZG, Umansky V.  Cancers (Basel). 2021 Feb 10;13(4):726. doi: 10.3390/cancers13040726. PMID: 33578808.

Human Adipose Tissue-Derived Mesenchymal Stromal Cells Inhibit CD4+ T Cell Proliferation and Induce Regulatory T Cells as Well as CD127 Expression on CD4+CD25+ T Cells. Fiori A, Uhlig S, Klueter H, Bieback K. Cells. 2021 Jan 1;10(1):58. doi: 10.3390/cells10010058.

2020

Comparison of Infection Risks and Clinical Outcomes in Patients with and without SARS-CoV-2 Lung Infection under Renin-Angiotensin-Aldosterone-System Blockade - Systematic Review and Meta-Analysis.
Chu C, Zeng S, Hasan AA, Hocher CF, Kraemer BK, Hocher B. Br J Clin Pharmacol. 2020 Nov 20. doi: 10.1111/bcp.14660. Epub ahead of print. PMID: 33217033.

Human Adipose Tissue-Derived Stromal Cells Suppress Human, but Not Murine Lymphocyte Proliferation, via Indoleamine 2,3-Dioxygenase Activity. Torres Crigna A, Uhlig S, Elvers-Hornung S, Klueter H, Bieback K. Cells. 2020 Nov 5;9(11):2419. doi: 10.3390/cells9112419.

Dance with the Devil: Stress Granules and Signaling in Antiviral Responses. Eiermann N, Haneke K, Sun Z, Stoecklin G, Ruggieri A. Viruses. 2020 Sep 4;12(9):984

Pro-angiogenic Activity Discriminates Human Adipose-Derived Stromal Cells From Retinal Pericytes: Considerations for Cell-Based Therapy of Diabetic Retinopathy. Kremer H, Gebauer J, Elvers-Hornung S, Uhlig S, Hammes HP, Beltramo E, Steeb L, Harmsen MC, Sticht C, Klueter H, Bieback K, Fiori A. Front Cell Dev Biol. 2020 Jun 9;8:387. doi: 10.3389/fcell.2020.00387. eCollection 2020. 

Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity.
Ni J, Wang X, Stojanovic A, Zhang Q, Wincher M, Bühler L, Arnold A, Correia MP, Winkler M, Koch PS, Sexl V, Höfer T, Cerwenka A. Immunity. 2020 Jun 16;52(6):1075

CDK1 couples proliferation with protein synthesis.
Haneke K, Schott J, Lindner D, Hollensen AK, Damgaard CK, Mongis C, Knop M, Palm W, Ruggieri A, Stoecklin G. J Cell Biol. 2020 Mar 2;219(3):e201906147

Recent advances in understanding mesenchymal stromal cells.
Rendra E, Scaccia E, Bieback K. F1000Res. 2020 Feb 27;9:F1000 Faculty Rev-156

The heat's on: nuclear stress bodies signal intron retention.
Erhardt S, Stoecklin G. EMBO J. 2020 Feb 3;39(3):e104154

Type 1 Treg cells promote the generation of CD8+ tissue-resident memory T cells.
Ferreira C, Barros L, Baptista M, Blankenhaus B, Barros A, Figueiredo-Campos P, Konjar Š, Lainé A, Kamenjarin N, Stojanovic A, Cerwenka A, Probst HC, Marie JC, Veldhoen M. Nat Immunol. 2020 Jul;21(7):766

Innate Cytokine Induced Early Release of IFNγ and CC Chemokines from Hypoxic Human NK Cells Is Independent of Glucose.
Velásquez SY, Himmelhan BS, Kassner N, Coulibaly A, Schulte J, Brohm K, Lindner HA. Cells. 2020 Mar 17;9(3):734

Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela Cells.
Hayes P, Fergus C, Ghanim M, Cirzi C, Burtnyak L, McGrenaghan CJ, Tuorto F, Nolan DP, Kelly VP. Nutrients. 2020 Mar 24;12(3):871

Pro-angiogenic Activity Discriminates Human Adipose-Derived Stromal Cells From Retinal Pericytes: Considerations for Cell-Based Therapy of Diabetic Retinopathy.
Kremer H, Gebauer J, Elvers-Hornung S, Uhlig S, Hammes HP, Beltramo E, Steeb L, Harmsen MC, Sticht C, Klueter H, Bieback K, Fiori A. Front Cell Dev Biol. 2020 Jun 9;8:387

Kontextspalte

Graduate Research Training Group (GRK) 2727/1

 

Associate Members

Steven Dooley, Prof. Dr.

Matthias Ebert, Prof. Dr.
- Elke Burgermeister, PD. Dr.

Sascha Gravius, Prof. Dr.

Jörg Heineke, Prof. Dr.

Stefan Klein, PD. Dr.

Bernhard Krämer, Prof. Dr.
- Benito Yard, Prof. Dr.

Holger Lindner, PD Dr.

Sonja Loges, Prof. Dr. Dr.

Jan Nicolay, Prof. Dr.

Michael Platten, Prof. Dr.

Lucas Schirmer, PD. Dr.

Astrid Schmieder, Prof. Dr.

Horst Schroten, Prof. Dr.

Christian Schwerk, Prof. Dr.

Jonathan Sleeman, Prof. Dr.

Marc Sütterlin, Prof. Dr.
- Kai Doberstein, Dr.
- Frederik Marmé, Prof. Dr.

Manfred Thiel, Prof. Dr.

Viktor Umansky, Prof. Dr