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Prof. Dr. Andreas Meyer-Lindenberg

Psychiatry, Neuroscience

The research interests of Prof. Meyer-Lindenberg focus on the development of novel treatments for severe psychiatric disorders, especially schizophrenia, through an application of multimodal neuroimaging, genetics and enviromics to characterize brain circuits underlying the risk for mental illness and cognitive dysfunction.

National and international joint research projects

BMBF: German Center of Mental Health (DZPG); Development funding duration: 2023 - 2025

BMBF: Removing language barriers in treating refugees (RELATER); Duration: 02/2019 - 01/2025

BMBF: COMorbidity Modeling via Integrative Transfer machine-learning in MENTal illness (COMMITMENT); Duration: 09/2019 - 05/2023

DFG: Heidelberg Pain Consortium SFB 1158: “From nociception to chronic pain: Structure- function properties of neural pathways and their reorganization” / 2nd funding period, Duration: 2019 – 2023

  • Project B09: “Regulatory brain circuits underlying bidirectional interactions between pain and depression”

EU: AIMS-2-trials: Autism Innovative Medicine Studies; Duration: 06/2018 - 05/2025

  • Site project Mannheim: “Biomarker discovery of autism and validation“

BMBF: Enhancing schizophrenia prevention and recovery through innovative treatments (ESPRIT); Duration:  09/2014 - 03/2022

Selected publications

  1. The non-ergodic nature of mental health and psychiatric disorders: implications for biomarker and diagnostic research.
    Meyer-Lindenberg A. (2023) World Psychiatry. 22(2):272-274.
  2. Ventral Striatal-Hippocampus Coupling During Reward Processing as a Stratification Biomarker for Psychotic Disorders.
    Schwarz K, Moessnang C, Schweiger JI, Harneit A, Schneider M, Chen J, Cao H, Schwarz E, Witt SH, Rietschel M, Nöthen M, Degenhardt F, Wackerhagen C, Erk S, Romanczuk-Seiferth N, Walter H, Tost H, Meyer-Lindenberg A. (2022) Biol Psychiatry. 91(2):216-225.
  3. Identifying multimodal signatures underlying the somatic comorbidity of psychosis: the COMMITMENT roadmap.
    Schwarz E, Alnæs D, Andreassen OA, Cao H, Chen J, Degenhardt F, Doncevic D, Dwyer D, Eils R, Erdmann J, Herrmann C, Hofmann-Apitius M, Kaufmann T, Koutsouleris N, Kodamullil AT, Khuntia A, Mucha S, Nöthen MM, Paul R, Pedersen ML, Quintero A, Schunkert H, Sharma A, Tost H, Westlye LT, Zhang Y, Meyer-Lindenberg A. (2021) Mol Psychiatry. 26(3):722-724.
  4. A neural mechanism for affective well-being: Subgenual cingulate cortex mediates real-life effects of nonexercise activity on energy.
    Reichert M, Braun U, Gan G, Reinhard I, Giurgiu M, Ma R, Zang Z, Hennig O, Koch ED, Wieland L, Schweiger J, Inta D, Hoell A, Akdeniz C, Zipf A, Ebner-Priemer UW, Tost H, Meyer-Lindenberg A. (2020) Science Advances. 6(45):eaaz8934. 
  5. Resilience and the brain: a key role for regulatory circuits linked to social stress and support.
    Holz NE, Tost H, Meyer-Lindenberg A. (2020) Molecular Psychiatry Feb;25(2):379-396. 
  6. Neural correlates of individual differences in affective benefit of real-life urban green space exposure.
    Tost H, Reichert M, Braun U, Reinhard I, Peters R, Lautenbach S, Hoell A, Schwarz E, Ebner-Priemer U, Zipf A, Meyer-Lindenberg A. (2019) Nature Neuroscience. 22(9):1389-139
  7. Environmental influence in the brain, human welfare and mental health.
    Tost H, Champagne FA, Meyer-Lindenberg A. (2015) Nature Neuroscience. 18(10):1421-31.
  8. Acute D2 receptor blockade induces rapid, reversible remodeling in human cortical-striatal circuits.
    Tost H, Braus DF, Hakimi S, Ruf M, Vollmert C, Hohn F, Meyer-Lindenberg A. (2010) Nature Neuroscience. 13(8):920-2.

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