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In the department of Experimental Pharmacology at the Medical Faculty Mannheim we look in several areas of G protein-mediated signal transduction in particular. These includes the cardiovascular functions of nucleoside diphosphate kinases (NDPKs), G protein-coupled receptors (GPCR), heterotrimeric G proteins, monomeric GTPases of the Rho family, as well as their regulators guanine nucleotide exchange factors (GEFs) and GTPase activating proteins (GAPs). We currently have three teams working on different subjects.

Cardiac Remodeling
Modulators of G-protein signaling