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PhD Students
![](/fileadmin/medma/_processed_/f/e/csm_Dennis_Agardy_9f21a4181a.jpg)
Dennis Agardy
Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, DKFZ, Heidelberg
d.agardy@
dkfz.de
Thesis: "Response and resistance to checkpoint blockade in melanoma brain metastases"
Project No. 14: "Response and Resistance to Checkpoint Blockade in melanoma brain metastases"
Lea Gärtner
Microvascular Biology and Pathobiology, Medical Faculty Mannheim, Heidelberg University
lea.gaertner@ medma.uni-heidelberg.de
Thesis: "Novel inhibitors of the transcriptional regulators Id1 and Id3, and their potential for the treatment of melanoma“
Project No. 3: "The role of systemic osteopontin and senescence in melanoma metastasis and therapy resistance”
![](/fileadmin/medma/_processed_/f/1/csm_Denise_Grieshober_dba63560d5.jpg)
Denise Grieshober
Vascular Oncology and Metastasis, DKFZ, Heidelberg
d.grieshober@
dkfz-heidelberg.de
Thesis: "The role of N-Fragment of Angiopoietin-like 4 during malignant melanoma
metastasis formation"
Project No. 4: "The role of N-Fragment of Angiopoietin-like 4 during malignant melanoma metastasis formation"
![](/fileadmin/medma/_processed_/d/6/csm_Verena_Haefele_69713eb82f.jpg)
Verena Häfele
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
verena.haefele@ medma.uni-heidelberg.de
Thesis: "Liver-specific endothelial mechanism of melanoma metastasis"
Project No. 8: "Pre-metastatic and immunologic conditioning of the hepatic vascular niche during melanoma progression"
![](/fileadmin/medma/_processed_/d/8/csm_Marvin_Hering_b499c07a15.jpg)
Marvin Hering
T Cell Metabolism (D140), DKFZ, Heidelberg
m.hering@
dkfz-heidelberg.de
Thesis: "Regulation of anti-tumor immune responses by nutrient availability in melanoma"
Project No. 15: "Regulation of anti-tumor immune responses by nutrient availability in melanoma"
Johannes Hoffmann
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
johannes.hoffmann@ medma.uni-heidelberg.de
Thesis: "Endotheliale Regulation der Metastasierung in Lymphknoten, Leber und Knochen"
Project No. 5: "The lymph node vascular niche in melanoma metastasis"
![](/fileadmin/medma/_processed_/7/f/csm_Tomas_Hofmann_8dfb58b14d.jpg)
Tomas Hofman
Immunobiochemistry, Medical Faculty Mannheim, Heidelberg University
tomas.hofman@
medma.uni-heidelberg.de
Thesis: "Defining innate immune checkpoints controlling NK cell recognition of melanoma cells”
Project No. 9: "Defining innate immune checkpoints controlling Natural Killer cell recognition of melanoma cells"
![](/fileadmin/medma/_processed_/1/0/csm_Samantha_Lasser_65c7abde05.jpg)
Samantha Lasser
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
samantha.Lasser@ medma.uni-heidelberg.de
Thesis: "Stimulation of myeloid cell-mediated immunosuppression via TLR signaling and its targeting in melanoma"
Project No. 11: "Stimulation of myeloid cell-mediated immunosuppression via TLR signaling and its targeting in melanoma"
Iris Müller
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
iris.mueller@ medma.uni-heidelberg.de
Thesis: „Inhibiting glucocorticoid receptor signaling in tumor-associated macrophages for antitumor immune response“
Project No. 10: "Role of the glucocorticoid-induced P2Y12/P2Y14+ G-protein coupled receptors for TAM in melanoma"
![](/fileadmin/medma/_processed_/6/7/csm_Siuwang_Ng_9176837546.jpg)
Siuwang Ng
Signaling and functional genomics (B110), DKFZ, Heidelberg
s.ng@
dkfz-heidelberg.de
Thesis: "Dissecting the role of Wnt signaling in melanoma"
Project No. 1: "Dissecting the role of Wnt signaling in melanoma"
![](/fileadmin/medma/_processed_/f/8/csm_img-sandra-pardo-valencia-208x208_0c82fb7282.jpg)
Sandra Pardo Valencia
Clinical Cooperation Unit Dermato-Oncology, DKFZ, Heidelberg
sandra.pardovalencia@ dkfz-heidelberg.de
Thesis: "Generation of T cells from iPS cells for melanoma treatment"
Project No. 13: "Differentiation of induced pluripotent stem cells into tumor antigen-specific T cells for melanoma immunotherapy"
![](/fileadmin/medma/_processed_/a/8/csm_Rafael_Saup_3d5673fc74.jpg)
Rafael Saup
Microvascular Biology and Pathobiology, Medical Faculty Mannheim, Heidelberg University
rafael.saup@ medma.uni-heidelberg.de
Thesis: "Cell-intrinsic and mircoenvironmental control of melanoma metastasis and therapy resistance”
Project No. 3: "The role of systemic osteopontin and senescence in melanoma metastasis and therapy resistance”
![](/fileadmin/medma/_processed_/2/9/csm_img-julia-schueler_f04c61b2f9.jpg)
Julia Schüler
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
julia.schueler@ medma.uni-heidelberg.de
Thesis: „Zur Analyse von angiokrinen und pro-adhäsiven Faktoren in der hepatischen vaskulären Nische im Rahmen der Lebermetastasierung des Malignen Melanoms“
Project No. 6: "Role of YAP/TAZ in the endothelium of melanoma brain metastasis“
![](/fileadmin/medma/_processed_/c/6/csm_Saskia_Tauch_7c62f99270.jpg)
Saskia Tauch
Division Signal Transduction and Growth Control, DKFZ, Heidelberg
s.tauch@
dkfz-heidelberg.de
Thesis: "Communication between tumor cells and fibroblasts in the tumor microenvironment during melanoma progression"
Project No. 2: "Communication between tumor cells and fibroblasts in the tumor microenvironment during melanoma progression"
![](/fileadmin/medma/_processed_/d/5/csm_Celine_Weller_cfa3bc7a8f.jpg)
Céline Weller
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
celine.weller@ medma.uni-heidelberg.de
Thesis: "Pre-metastatic and immunologic conditioning of the hepatic vascular niche during melanoma progression"
Project No. 8: "Pre-metastatic and immunologic conditioning of the hepatic vascular niche during melanoma progression"
![](/fileadmin/medma/_processed_/d/3/csm_Melanie_Wiecken_4fa31ce62c.jpg)
Melanie Wiecken
Section of Dermatological Oncology, Dept. Dermatology, University Medical Center Heidelberg, and National Center of Tumor Diseases (NCT)
melanie.wiecken@ uni-heidelberg.de
Thesis: "The role of the immune checkpoints LAG-3 and TIM-3 in melanoma"
Project No. 12: "The role of the immune checkpoints LAG-3 and TIM-3 for immunotherapy of melanoma"
MD Students
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Ihor Arkhypov
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
ihor.arkhypov@ medma.uni-heidelberg.de
Thesis: "Role of tumor-derived exosomes in induction of immunosuppressive myeloid cells in melanoma patients"
Project No. 11: "Stimulation of myeloid cell-mediated immunosuppression via TLR signaling and its targeting in melanoma"
Tinja Baljkas
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
tinja.baljkas@ medma.uni-heidelberg.de
Thesis: „Zur Rolle des Transkriptionsfaktors GATA-4 und assoziierter Signalwege im Lebersinusendothel bei der Entstehung der Leberfibrose“
Project No. 5: "The lymph node vascular niche in melanoma metastasis"
![](/fileadmin/medma/_processed_/c/b/csm_Anja_Gampp_a7cbddff29.jpg)
Anja Gampp
Vascular Oncology and Metastasis, DKFZ, Heidelberg
anja.gampp@
nct-heidelberg.de
Thesis: "Die epigenetische Reprogrammierung von Endothelzellen während des Metastasierungsprozesses"
Project No. 4: "The role of N-Fragment of Angiopoietin-like 4 during malignant melanoma metastasis formation"
![](/fileadmin/medma/_processed_/3/a/csm_img-julia-gellert-208x208_a1c0439145.jpg)
Julia Gellert
Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, DKFZ, Heidelberg
julia.gellert@ dkfz-heidelberg.de
Thesis: “Characterization of the melanoma-specific T cell response in the CNS tumor microenvironment under immunotherapy“
Project No. 14: "Response and resistance to checkpoint blockade in melanoma brain metastases"
![](/fileadmin/medma/_processed_/4/1/csm_img-nils-hebach-208x208_e6ce74823a.jpg)
Nils Hebach
Clinical Cooperation Unit Neuro-Oncology, DKFZ, Heidelberg
nils.hebach@ dkfz-heidelberg.de
Thesis: „T cell homing and microenvironmental cues in melanoma brain metastasis“
Project No. 7: "Mechanisms of T cell homing and function in melanoma brain metastases"
Joschka Heil
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
joschka.heil@ medma.uni-heidelberg.de
Thesis: "Einfluss von endothelialer β-Catenin Aktivierung auf die Stammzell-Nische im Knochenmark"
Project No. 5: "The lymph node vascular niche in melanoma metastasis"
![](/fileadmin/medma/_processed_/f/0/csm_img-katharina-held-208x208_e9f221ed9c.jpg)
Katharina Held
Microvascular Biology and Pathobiology, Medical Faculty Mannheim, Heidelberg University
katharina.held@ medma.uni-heidelberg.de
Thesis: "Erforschung der molekularen Mechanismen der Resistenzenbildung von Melanomen gegen kombinierte Therapie mit BRAF- und MEK-Inhibitoren"
Project No. 3: "The role of systemic osteopontin and senescence in melanoma metastasis and therapy resistance"
![](/fileadmin/medma/_processed_/3/d/csm_Foto_Anna_Irkens_e934fcb048.jpg)
Anna Lena Irkens
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
anna.Irkens@ medma.uni-heidelberg.de
Thesis: „Mechanismen und therapeutische Modulation der Stabilin-mediierten Scavengingfunktion bei der hepatischen Melanommetastasierung“
Project No. 8: “Pre-metastatic and immunologic conditioning of the hepatic vascular niche during melanoma progression"
![](/fileadmin/medma/_processed_/0/5/csm_Anna_Jauch_b8974a2e41.jpg)
Anna Jauch
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
anna.jauch@ medma.uni-heidelberg.de
Thesis: "Bedeutung von LYVE1 in der hepatischen vaskulären Nische für die Melanom-metastasierung in die Leber"
Project No. 8: "Pre-metastatic and immunologic conditioning of the hepatic vascular niche during melanoma progression"
![](/fileadmin/medma/_processed_/3/2/csm_Niklas_Kehl_98822b0dee.jpg)
Niklas Kehl
Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, DKFZ, Heidelberg
niklas.kehl@ dkfz-heidelberg.de
Thesis: "Establishment of a preclinical adoptive transfer model against immunogenic gene fusions"
Project No. 14: "Response and resistance to checkpoint blockade in melanoma brain metastases"
Christof Kirkamm
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
christof.kirkamm@ medma.uni-heidelberg.de
Thesis: "Biochemical and functional characterization of potential ligands of Stabilin-1 and Stabilin-2"
Project No. 8: "Pre-metastatic and immunologic conditioning of the hepatic vascular niche during melanoma progression"
![](/fileadmin/medma/_processed_/f/6/csm_img-philipp-koopmann_e0bb27ad98.jpg)
Philipp Koopmann
Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, DKFZ, Heidelberg
philipp.koopmann@ dkfz-heidelberg.de
Thesis: „Identifikation und Charakterisierung tumorreaktiver T-Zellen in Hirnmetastasen“
Project No. 14: "Response and resistance to checkpoint blockade in melanoma brain metastases"
![](/fileadmin/medma/_processed_/b/f/csm_img-alisa-lepper-208x208_6f003b8e09.jpg)
Alisa Lepper
Clinical Cooperation Unit Dermato-Oncology, DKFZ, Heidelberg
alisa.lepper@ dkfz-heidelberg.de
Thesis: "Das Verhalten von myeloid-derived suppressor cells (MDSCs) und T-Zellen bei Melanompatienten mit autoimmunen Nebenwirkungen unter Immuncheckpoint-Inhibitor Therapie"
Project No. 13: "Differentiation of induced pluripotent stem cells into tumor antigen-specific T cells for melanoma immunotherapy"
![](/fileadmin/medma/_processed_/9/f/csm_Marcel_Mueller_51e3c4638c.jpg)
Marcel Müller
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
marcel.mueller@ medma.uni-heidelberg.de
Thesis: "Die Rolle des Glukokortikoid-Rezeptors auf myeloiden Zellen in der Wundheilung"
Project No. 10: "Role of the glucocorticoid-induced P2Y12/P2Y14+ G-protein coupled receptors for TAM in melanoma"
![](/fileadmin/medma/_processed_/4/2/csm_Ana_Olsavszky_ee6913dc4a.jpg)
Ana Olsavszky
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
ana.olsavszky@ medma.uni-heidelberg.de
Thesis: "Bedeutung der hepatischen vaskulären Nische bei der Melanommetastasierung"
Project No. 8: "Pre-metastatic and immunologic conditioning of the hepatic vascular niche during melanoma progression"
![](/fileadmin/medma/_processed_/3/a/csm_Vera_Petrova_37df145c71.jpg)
Vera Petrova
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
vera.petrova@ medma.uni-heidelberg.de
Thesis: "The immuno-suppressive capacity of different subsets of myeloid-derived suppressor cells (MDSC) in melanoma patients under targeted immunotherapies"
Project No. 11: "Stimulation of myeloid cell-mediated immunosuppression via TLR signaling and its targeting in melanoma"
Kajetan Sandorski
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
kajetan.sandorski@ medma.uni-heidelberg.de
Thesis: "Einfluss von konstitutiver beta-Catenin Aktivierung auf die Differenzierung von Lebersinusendothelzellen und die Metastasierung des Malignen Melanoms"
Project No. 5: "The lymph node vascular niche in melanoma metastasis"
![](/fileadmin/medma/_processed_/d/2/csm_img-niklas-straub_e3b972e0cc.jpg)
Niklas Straub
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
niklas.straub@ medma.uni-heidelberg.de
Thesis: "Influence of inflammatory monocytes and neutrophil granulocytes on hepatic melanoma metastasis“
Project No. 8: "Pre-metastatic and immunologic conditioning of the hepatic vascular niche during melanoma progression"
![](/fileadmin/medma/_processed_/1/a/csm_img-maximilian-suhayda-208x208_843a65de57.jpg)
Maximilian Suhayda
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
maximilian.suhayda@ medma.uni-heidelberg.de
Thesis: "Characterization of molecular co-regulators for hepatic vascular niche differentiation and liver function"
Project No. 5: "The lymph node vascular niche in melanoma metastasis"
![](/fileadmin/medma/_processed_/d/7/csm_Cedric_Tehranian_1e95fa078c.jpg)
Cedric Tehranian
Clinical Cooperation Unit Neuro-Oncology, DKFZ, Heidelberg
c.tehranian@ dkfz-heidelberg.de
Thesis: "Targeting the P13K-AKT-mTor pathway in melanoma brain metastasis"
Project No. 7: "Mechanisms of T cell homing and function in melanoma brain metastases"
![](/fileadmin/medma/_processed_/8/4/csm_img-yang-tuo-208x208_416c094e86.jpg)
Yang Tuo
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
yang.tuo@ medma.uni-heidelberg.de
Thesis: "Zur Rolle des Notch-Signalwegs im Lebersinusendothel bei der Entstehung der Leberfibrose"
Project No. 5: "The lymph node vascular niche in melanoma metastasis"
Associated PhD Students
![](/fileadmin/medma/_processed_/8/8/csm_Bianca_Dietsch_7f35c06038.jpg)
Bianca Dietsch
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
bianca.dietsch@ medma.uni-heidelberg.de
Thesis: "Tumorintrinsische Promotoren der hepatischen Metastasierung"
Project No. 8: "Pre-metastatic and immunologic conditioning of the hepatic vascular niche during melanoma progression"
![](/fileadmin/medma/_processed_/3/a/csm_img-feyza-gul-ozbay-kurt_4ba9749afa.png)
Feyza Gul Ozbay Kurt
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
feyza.kurt@ medma.uni-heidelberg.de
Thesis: "Targeting myeloid cell-mediated immunosuppression in malignant melanoma"
Project No. 11: "Stimulation of myeloid cell-mediated immunosuppression via TLR signaling and its targeting in melanoma"
![](/fileadmin/medma/_processed_/4/a/csm_Theresa_Staniczek_c5cce3439f.jpg)
Theresa Staniczek
Department of Dermatology, Venereology and Allergology, UMM, Mannheim
theresa.staniczek@ medma.uni-heidelberg.de
Thesis: "Endotheliale Regulation der Leberhomöostase und Hepatokarzinogenese"
Project No. 8: "Pre-metastatic and immunologic conditioning of the hepatic vascular niche during melanoma progression"
Tamara Steinfass
Clinical Cooperation Unit Dermato-Oncology, DKFZ, Heidelberg
t.steinfass@
dkfz-heidelberg.de
Thesis: "SETDB1 in Melanom-Therapie Resistenz"
Project No. 13: "Differentiation of induced pluripotent stem cells into tumor antigen-specific T cells for melanoma immunotherapy"
![](/fileadmin/medma/Institute/RTG2099/yiman-wang-quadrat.jpg)
Yiman Wang
Clinical Cooperation Unit Dermato-Oncology, DKFZ, Heidelberg
yiman.wang@ dkfz-heidelberg.de
Thesis: “Characterization and functional role of neural crest-associated genes involved in melanoma therapy-induced resistance”
Project No. 13: "Differentiation of induced pluripotent stem cells into tumor antigen-specific T cells for melanoma immunotherapy"